Corynebacterium glutamicum, Escherichia coli, and Saccharomyces cerevisiae in particular,
have become established as important industrial workhorses in biotechnology. Recent years …

The production of aromatic amino acids using fermentation processes with recombinant
microorganisms can be an advantageous approach to reach their global demands. In …

In order to decrease carbon emissions and negative environmental impacts of various
pollutants, more bulk and/or fine chemicals are produced by bioprocesses, replacing the …

Efficient biosynthesis of l-tyrosine from glucose is necessary to make biological production
economically viable. To this end, we designed and constructed a modular biosynthetic …

Chemical synthesis is a well established route for producing many chemicals on a large
scale, but some drawbacks still exist in this process, such as unstable intermediates …

Phenolics are a class of plant-derived natural secondary metabolites with good anticancer,
anti-inflammatory, antimicrobial and antioxidant activities. In addition to being natural health …

Shikimic acid is a key intermediate for the synthesis of the antiviral drug oseltamivir
(Tamiflu®). Shikimic acid can be produced via chemical synthesis, microbial fermentation …

Biotechnological production of phenolic acids is attracting increased interest due to their
superior antioxidant activity, as well as other antimicrobial, dietary, and health benefits. As …

Corynebacterium glutamicum with the ability to simultaneously utilize glucose/pentose
mixed sugars was metabolically engineered to overproduce shikimate, a valuable …

Recombinant strains of Escherichia coli K-12 for the production of the three aromatic amino
acids (l-phenylalanine, l-tryptophan, l-tyrosine) have been constructed. The largest demand …