Nitric Oxide (NO) is a highly diffusible, ubiquitous signaling molecule and a free radical that
is naturally synthesized by our body. The pleiotropic effects of NO in biological systems are …

Ever since their discoveries, the Wnt pathways have been consistently associated with key
features of cellular development, including metabolism, structure and cell fate. The three …

Bipolar disorder (BD) is a psychiatric condition characterized by depressive and manic
episodes that affect 2% of the world population. The first-line long-term treatment for mood …

Since its discovery, Wnt signaling has been shown to be one of the most crucial
morphogens in development and during the maturation of central nervous system. Its action …

Mounting evidence indicates that Wnt signaling is relevant to pathophysiology of diverse
mental illnesses including schizophrenia, bipolar disorder, and autism spectrum disorder. In …

Synaptic transmission is a dynamic process that requires precise regulation. Early in life, we
must be able to forge appropriate connections (add and remove) to control our behavior …

Wnt signaling plays a role in synaptic plasticity, but the specific cellular events and
molecular components involved in Wnt signaling-mediated synaptic plasticity are not well …

Neurodegenerative diseases (NDs) are conditions characterized by sensory, motor, and
cognitive impairments due to alterations in the structure and function of neurons in the …

Structural plasticity of synapses correlates with changes in synaptic strength. Dynamic
modifications in dendritic spine number and size are crucial for long-term potentiation (LTP) …

Wnt signaling plays an essential role in cellular processes like development, maturation,
and function maintenance. Xenopus laevis oocytes are a suitable model to study not only …