Osteoarthritis is a common age-related joint degenerative disease. Pain, swelling, brief
morning stiffness, and functional limitations are its main characteristics. There are still no …

Pentosan polysulfate (PPS), a small semi-synthetic highly sulfated heparan sulfate (HS)-like
molecule, shares many of the interactive properties of HS. The aim of this review was to …

The therapeutic potential of the mesenchymal stromal cell (MSC) secretome, consisting of all
molecules secreted by MSCs, is intensively studied. MSCs can be readily isolated …

The stem cells, owing to their special characteristics like self‐renewal, multiplication,
homing, immunomodulation, anti‐inflammatory, and dedifferentiation are considered to carry …

Abstract Background Sodium pentosan polysulfate (NaPPS) was testified as a
chondroprotective drug in with a detailed rationale of the disease-modifying activity. This …

This chapter proposes a proactive, preventive multimodal pain management strategy,
introduces a “tiered decision tree” to prioritize evidence‐based therapy, and critically …

Pentosan polysulfate sodium (PPS) is a heparin-like polysaccharide that is applied as a
therapeutic treatment for osteoarthritis (OA) in animals. This study investigated the efficacy of …

Pentosan polysulfate (PPS) is a semi-synthetic sulfated polysaccharide compound which
has been shown the benefits on therapeutic treatment for osteoarthritis (OA) and has been …

Mesenchymal stem cells (MSCs) have characteristic properties, the expression of which is
being determined by the available microenvironment/niche. Extensive ex vivo studies have …

Among various joint affections, osteoarthritis is one of the most common joint problems
reported in animals. Currently, no effective treatment is available that can treat the condition …