Solid-state NMR spectroscopy is one of the most commonly used techniques to study the
atomic-resolution structure and dynamics of various chemical, biological, material, and …

Since the first pioneering studies on small deuterated peptides dating more than 20 years
ago, 1H detection has evolved into the most efficient approach for investigation of …

In the last two decades, solid-state nuclear magnetic resonance (ssNMR) spectroscopy has
transformed from a spectroscopic technique investigating small molecules and industrial …

Background & Aims JNJ-56136379 (JNJ-6379), a capsid assembly modulator that blocks
hepatitis B virus (HBV) replication, was well tolerated and demonstrated dose-proportional …

The highly infectious disease COVID-19 caused by the Betacoronavirus SARS-CoV-2 poses
a severe threat to humanity and demands the redirection of scientific efforts and criteria to …

The standard of care for the treatment of chronic hepatitis B (CHB) is typically lifelong
treatment with nucleos (t) ide analogs (NAs), which suppress viral replication and provide …

Cell-free protein synthesis (CFPS) systems are gaining more importance as universal tools
for basic research, applied sciences, and product development with new technologies …

Experimentally determined protein structures often feature missing domains. One example is
the C‐terminal domain (CTD) of the hepatitis B virus capsid protein, a functionally central …

Techniques for atomic-resolution structural biology have evolved during the past several
decades. Breakthroughs in instrumentation, sample preparation, and data analysis that …

Structural virology reveals the architecture underlying infection. While notably electron
microscopy images have provided an atomic view on viruses which profoundly changed our …