Abstract P-glycoprotein (P-gp) is a drug efflux transporter that triggers doxorubicin (DOX)
resistance. In this review, we highlight the molecular avenues regulating P-gp, such as Nrf2 …

ABSTRACT Introduction: Solid lipid nanoparticles (SLNs) are solid core lipid nanocarriers,
which can hold both hydrophilic and hydrophobic drugs. They can be made up of …

D-ɑ-tocopheryl polyethylene glycol succinate (Vitamin E TPGS or TPGS) has been
approved by FDA as a safe adjuvant and widely used in drug delivery systems. The …

The oral route is a preferred method of drug administration, though achieving effective drug
delivery and minimizing off-target side effects is often challenging. Formulation into …

Nanomedicine involves the use of nanoparticles for therapeutic and diagnostic purposes.
During the past two decades, a growing number of nanomedicines have received regulatory …

Chemical and enzymatic barriers in the gastrointestinal (GI) tract hamper the oral delivery of
many labile drugs. The GI epithelium also contributes to poor permeability for numerous …

Background Metastasis causes the most breast cancer-related deaths in women. Here, we
investigated the antitumor effect of solid lipid nanoparticles (SLN-DTX) when used in the …

Solid lipid nanoparticles (SLNs), the spheroidal-shaped, colloids state lipophilic-natured,
innovative nanoscale particulate materials, are being concurrently prepared by the quality …

Oral squamous cell carcinoma (OSCC) is the most common type of oral cancer; it involves
damage to oral epithelial cells due to accumulation of multiple genetic mutations in the cells …

Nanocarriers, due to their unique features, are of increased interest among researchers
working with pharmaceutical formulations. Polymeric nanoparticles and nanocapsules …