The present review aimed to outline different types of RNAs in cancer diagnostics and
treatment, and to provide novel insights into their clinical applications. RNAs, including …

The drug discovery process starts with identification of a disease-modifying target. This
critical step traditionally begins with manual investigation of scientific literature and …

Epigallocatechin gallate (EGCG), also known as epigallocatechin-3-gallate, is an ester of
epigallocatechin and gallic acid. EGCG, abundantly found in tea, is a polyphenolic flavonoid …

Multidrug resistance (MDR) is one of the primary factors that produces treatment failure in
patients receiving cancer chemotherapy. MDR is a complex multifactorial phenomenon …

Long noncoding RNAs (lncRNAs) constitute large portions of the mammalian transcriptome
which appeared as a fundamental player, regulating various cellular mechanisms. LncRNAs …

Noncoding RNAs are functional transcripts that are not translated into proteins. They
represent the largest portion of the human transcriptome and have been shown to regulate …

Genetic studies traditionally focus on DNA as the molecule that passes information on from
parents to their offspring. Changes in the DNA code alter heritable information and can more …

Three types of highly promising small RNA therapeutics, namely, small interfering RNAs
(siRNAs), microRNAs (miRNAs) and the RNA subtype of antisense oligonucleotides (ASOs) …

The increasing knowledge in the field of oncoimmunology has led to extensive research into
tumor immune landscape and a plethora of clinical immunotherapy trials in cancer patients …

Methyl-7-guanosine (m7G)“capping” of coding and some noncoding RNAs is critical for their
maturation and subsequent activity. Here, we discovered that eukaryotic translation initiation …