Involvement of machine learning tools in healthcare decision making

SMDAC Jayatilake… - Journal of healthcare …, 2021 - Wiley Online Library
In the present day, there are many diseases which need to be identified at their early stages
to start relevant treatments. If not, they could be uncurable and deadly. Due to this reason …

[HTML][HTML] A comprehensive review of artificial intelligence and network based approaches to drug repurposing in Covid-19

F Ahmed, AM Soomro, ARC Salih… - Biomedicine & …, 2022 - Elsevier
Conventional drug discovery and development is tedious and time-taking process; because
of which it has failed to keep the required pace to mitigate threats and cater demands of viral …

[HTML][HTML] Drug repurposing strategy (DRS): Emerging approach to identify potential therapeutics for treatment of novel coronavirus infection

BM Sahoo, BVV Ravi Kumar, J Sruti… - Frontiers in Molecular …, 2021 - frontiersin.org
Drug repurposing is also termed as drug repositioning or therapeutic switching. This method
is applied to identify the novel therapeutic agents from the existing FDA approved clinically …

[HTML][HTML] A systematic review of computational approaches to understand cancer biology for informed drug repurposing

F Ahmed, A Samantasinghar, AM Soomro, S Kim… - Journal of Biomedical …, 2023 - Elsevier
Cancer is the second leading cause of death globally, trailing only heart disease. In the
United States alone, 1.9 million new cancer cases and 609,360 deaths were recorded for …

Artificial intelligence in early drug discovery enabling precision medicine

F Boniolo, E Dorigatti, AJ Ohnmacht… - Expert Opinion on …, 2021 - Taylor & Francis
Introduction: Precision medicine is the concept of treating diseases based on environmental
factors, lifestyles, and molecular profiles of patients. This approach has been found to …

[HTML][HTML] Advanced computational methodologies used in the discovery of new natural anticancer compounds

VP Chavda, YN Ertas, V Walhekar, D Modh… - Frontiers in …, 2021 - frontiersin.org
Natural chemical compounds have been widely investigated for their programmed necrosis
causing characteristics. One of the conventional methods for screening such compounds is …

Systems biology based drug repositioning for development of cancer therapy

B Turanli, O Altay, J Borén, H Turkez, J Nielsen… - Seminars in cancer …, 2021 - Elsevier
Drug repositioning is a powerful method that can assists the conventional drug discovery
process by using existing drugs for treatment of a disease rather than its original indication …

A paradigm shift in medicine: A comprehensive review of network-based approaches

F Conte, G Fiscon, V Licursi, D Bizzarri, T D'Antò… - … et Biophysica Acta (BBA …, 2020 - Elsevier
Network medicine is a rapidly evolving new field of medical research, which combines
principles and approaches of systems biology and network science, holding the promise to …

Repurposing of plant alkaloids for cancer therapy: Pharmacology and toxicology

T Efferth, F Oesch - Seminars in Cancer Biology, 2021 - Elsevier
Drug repurposing (or repositioning) is an emerging concept to use old drugs for new
treatment indications. Phytochemicals isolated from medicinal plants have been largely …

Drug repositioning through integration of prior knowledge and projections of drugs and diseases

P Xuan, Y Cao, T Zhang, X Wang, S Pan… - Bioinformatics, 2019 - academic.oup.com
Motivation Identifying and developing novel therapeutic effects for existing drugs contributes
to reduction of drug development costs. Most of the previous methods focus on integration of …