Cellular exposure to ionizing radiation leads to oxidizing events that alter atomic structure
through direct interactions of radiation with target macromolecules or via products of water …

An “abscopal” effect occurs when localized irradiation perturbs the organism as a whole,
with consequences that can be either beneficial or detrimental. Mechanistic explanations of …

The present system of radiation protection assumes that exposure at low doses and/or low
dose-rates leads to health risks linearly related to the dose. They are evaluated by a …

Non-DNA targeted effects of ionising radiation, which include genomic instability, and a
variety of bystander effects including abscopal effects and bystander mediated adaptive …

Significance: Epidemiological and animal studies have demonstrated a close link between
maternal nutrition and chronic metabolic disease in children and adults. Compelling …

Purpose: To review the data concerning the role of endogenously generated reactive
oxygen species (ROS) in the non-targeted ionizing radiation (IR) effects and in …

There is much evidence supporting the existence of bystander effects in cells that were
never exposed to radiation. Directly irradiated cells and bystander cells can communicate …

The brain is the major dose-limiting organ in patients undergoing radiotherapy for assorted
conditions. Radiation-induced brain injury is common and mainly occurs in patients …

It is becoming increasingly clear that cells exposed to ionizing radiation (IR) and other
genotoxic agents (targeted cells) can communicate their DNA damage response (DDR) …

The author is ready to assert that practically none of the readers of this book will ever
happen to deal with large doses of radiation. But the author, without a shadow of a doubt …