Given that natural selection is so powerful at optimizing complex adaptations, why does it
seem unable to eliminate genes (susceptibility alleles) that predispose to common, harmful …

Neuroscience is a multidisciplinary effort to understand the structures and functions of the
brain and brain-mind relations. This effort results in an increasing amount of data, generated …

Systems engineering (SE) is experiencing a significant expansion that encompasses
increasingly complex systems. However, a common body of knowledge on how to apply …

We assert that one of the examples used by Keller & Miller (K&M), namely, autism, is indeed
common, and heritable, but we question whether it is harmful. We provide a brief review of …

The mutation-selection hypothesis may extend to understanding normal personality
variation. Traits such as emotional stability, agreeableness, and conscientiousness figure …

Biological psychiatry has more and more directed it's focus on the involvement of genes and
molecules in mental health and disease. On these levels, new approaches in other medical …

Grouping severe mental disorders into a global category is likely to lead to a “theory of
everything” which forcefully explains everything and nothing. Speculation even at the …

Deep brain stimulation (DBS) has had a remarkable success in treating a range of
neurological and psychiatric conditions. However, efficacy remains suboptimal and patients …

We describe delusional disorder–jealous type (“morbid jealousy”) with the adaptationist
perspective used by Darwinian psychiatrists and evolutionary psychologists to explain the …

Keller & Miller (K&M) make a persuasive case for the role of mutation-selection balance in
the persistence of such disorders as schizophrenia. However, there is evidence relating …