Decades of research on the human papillomavirus oncogenes, E6 and E7, have given us
huge amounts of data on their expression, functions and structures. We know much about …

Evidence suggests that beta human papillomaviruses (HPVs), together with ultraviolet
radiation, contribute to the development of cutaneous squamous cell carcinoma. Beta HPVs …

Highlights•Viral infections cause approximately 12% of all human cancers.•Viral cancers
represent rare outcomes of frequent infections.•Oncogenicity of viral proteins reflects their …

A murine papillomavirus, MmuPV1, infects both cutaneous and mucosal epithelia of
laboratory mice and can be used to model high-risk human papillomavirus (HPV) infection …

Human papillomaviruses (HPV) cause persistent infections by modulating epithelial
homeostasis in cells of the infected basal layer. Using FUCCI and cell-cell competition …

Epidemiological and biological studies provide several lines of evidence for the involvement
of cutaneous beta human papillomaviruses (HPVs), together with ultraviolet (UV) radiation …

Notch receptors participate in a conserved pathway in which ligands expressed on
neighboring cells trigger a series of proteolytic cleavages that allow the intracellular portion …

Papillomaviruses exclusively infect stratified epithelial tissues and cause chronic infections.
To achieve this, infected cells must remain in the epithelial basal layer alongside their …

There is still controversy in the scientific field about whether certain types of cutaneous
human papillomaviruses (HPVs) are causally involved in the development of non-melanoma …

Papillomaviruses replicate and cause disease in stratified squamous epithelia. Epithelial
differentiation is essential for the progression of papillomavirus replication, but differentiation …