[HTML][HTML] Dopamine D3 receptor: A neglected participant in Parkinson Disease pathogenesis and treatment?

P Yang, JS Perlmutter, TLS Benzinger, JC Morris… - Ageing research …, 2020 - Elsevier
Parkinson disease (PD) is a neurodegenerative disorder characterized by motor and non-
motor symptoms which relentlessly and progressively lead to substantial disability and …

Dopamine transporter deficient rodents: perspectives and limitations for neuroscience

A Savchenko, G Targa, Z Fesenko, D Leo… - Biomolecules, 2023 - mdpi.com
The key element of dopamine (DA) neurotransmission is undoubtedly DA transporter (DAT),
a transmembrane protein responsible for the synaptic reuptake of the mediator. Changes in …

Vortioxetine ameliorates motor and cognitive impairments in the rotenone-induced Parkinson's disease via targeting TLR-2 mediated neuroinflammation

DN Samur, G Akçay, S Yıldırım, A Özkan, T Çeker… - …, 2022 - Elsevier
Parkinson's disease (PD) is characterized by motor and non-motor symptoms associated
with dopaminergic and non-dopaminergic injury. Vortioxetine is a multimodal serotonergic …

AgRP neurons control structure and function of the medial prefrontal cortex

B Stutz, MJ Waterson, M Šestan-Peša, MO Dietrich… - Molecular …, 2022 - nature.com
Hypothalamic agouti-related peptide and neuropeptide Y-expressing (AgRP) neurons have
a critical role in both feeding and non-feeding behaviors of newborn, adolescent, and adult …

Behaviorally penetrant, anomalous dopamine efflux exposes sex and circuit dependent regulation of dopamine transporters

A Stewart, FP Mayer, R Gowrishankar, GL Davis… - Molecular …, 2022 - nature.com
Virtually all neuropsychiatric disorders display sex differences in prevalence, age of onset,
and/or clinical symptomology. Although altered dopamine (DA) signaling is a feature of …

[HTML][HTML] Reactive mesoporous silica nanoparticles loaded with limonene for improving physical and mental health of mice at simulated microgravity condition

Z Lu, J Wang, L Qu, G Kan, T Zhang, J Shen, Y Li… - Bioactive Materials, 2020 - Elsevier
Astronauts are under high stress for a long time because of the microgravity condition, which
leads to anxiety, affects their learning and memory abilities, and seriously impairs the health …

Targeting the intracellular signaling “STOP” and “GO” pathways for the treatment of alcohol use disorders

D Ron, A Berger - Psychopharmacology, 2018 - Springer
In recent years, research has identified the molecular and neural substrates underlying the
transition of moderate “social” consumption of alcohol to the characteristic alcohol use …

A new paradigm for training hyperactive dopamine transporter knockout rats: influence of novel stimuli on object recognition

NP Kurzina, AB Volnova, IY Aristova… - Frontiers in Behavioral …, 2021 - frontiersin.org
Attention deficit hyperactivity disorder (ADHD) is believed to be connected with a high level
of hyperactivity caused by alterations of the control of dopaminergic transmission in the …

[HTML][HTML] Improvements of cognitive functions in mice heavily infected by Angiostrongylus cantonensis after treatment with albendazole, dexamethasone, or co-therapy

KY Jhan, CJ Cheng, CJ Chou, SM Jung, GJ Lai… - Journal of Microbiology …, 2022 - Elsevier
Angiostrongylus cantonensis, the causative agent of human eosinophilic meningitis and
eosinophilic meningoencepalitis, has been reported to cause cognitive impairments in the …

[HTML][HTML] Acute paraoxon-induced neurotoxicity in a mouse survival model: Oxidative stress, dopaminergic system alterations and memory deficits

E Urquizu, S Paratusic, J Goyenechea… - International journal of …, 2024 - mdpi.com
The secondary neurotoxicity induced by severe organophosphorus (OP) poisoning,
including paraoxon (POX), is associated with cognitive impairments in survivors, who …