Background and purpose Chronic liver injury, caused by various aetiologies, causes
recurrent tissue damage, culminating in decreased liver regenerative ability and resulting in …

Aims Acute lung inflammation, particularly acute respiratory distress syndrome (ARDS), is
caused by a variety of pathogens including bacteria and viruses. β-Glucans have been …

In idiopathic pulmonary fibrosis (IPF), excessive collagen deposition predisposes to
irreversible lung function decline, respiratory failure, and ultimately death. Due to the limited …

Ulcerative colitis (UC) is an intestinal inflammatory disease characterised by the loss of
intestinal crypts, edema, mucosal ulceration, and infiltration of inflammatory cells in the …

Liver diseases caused by viral infections, alcoholism, drugs, or chemical poisons are a
significant health problem: Liver diseases are a leading contributor to mortality, with …

The arylsulfonamides were synthesized from aryl sulfonyl chloride and aromatic amines in
dichloromethane in the presence of pyridine. The aryne chemistry was used to prepare …

Idiopathic pulmonary fibrosis (IPF) is a devastating interstitial lung disorder characterized by
the accumulation of extracellular matrix and collagen, resulting in significant parenchymal …

To discover novel anti-fibrotic agents, a series of UDCA-aminopyrimidine hybrids were
designed and synthesized as potent ATX inhibitors by molecular hybridization strategy. The …

Aim Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive condition with unknown
aetiology that causes the lung parenchyma to scar incessantly, lowering the quality of life …

Acute myocarditis, also known as myocardial inflammation, is a self-limited condition caused
by systemic infection with cardiotropic pathogens, primarily viruses, bacteria, or fungi …