Simple Summary Skeletal muscle mass is an important economic trait, and muscle
development and growth is a crucial factor to supply enough meat for human consumption …

Abstract Glycogen synthase kinase‐3 (GSK3) is a highly evolutionarily conserved
serine/threonine protein kinase first identified as an enzyme that regulates glycogen …

Insufficient pancreatic β-cell mass or function results in diabetes mellitus. While significant
progress has been made in regulating insulin secretion from β-cells in diabetic patients, no …

Myoblast fusion is a critical process that contributes to the growth of muscle during
development and to the regeneration of myofibers upon injury. Myoblasts fuse with each …

Non‐technical summary During exercise, skeletal muscle performance depends in great
part on the use of aerobic metabolism to supply the energetic demand of contractions …

Wingless/integrase-1 (WNT) signaling is a key pathway regulating various aspects of
embryonic development; however it also underlies several pathological conditions in man …

Myogenesis is a complex and tightly regulated process, the end result of which is the
formation of a multinucleated myofibre with contractile capability. Typically, this process is …

Lithium is most well-known for its mood-stabilizing effects in the treatment of bipolar
disorder. Due to its narrow therapeutic window (0.5-1.2 mM serum concentration), there is a …

Inhibiting glycogen synthase kinase 3 (GSK3) improves muscle function, metabolism, and
bone health in many diseases and conditions; however, whether GSK3 should be targeted …

5-Fluorouracil (5-Fu) is commonly used in the chemotherapy of colorectal cancer (CRC), but
resistance to 5-Fu occurs in most cases, allowing cancer progression. Suppressing ABCB1 …