[HTML][HTML] Computational methods to predict protein aggregation
In most cases, protein aggregation stems from the establishment of non-native
intermolecular contacts. The formation of insoluble protein aggregates is associated with …
intermolecular contacts. The formation of insoluble protein aggregates is associated with …
Relevance of electrostatic charges in compactness, aggregation, and phase separation of intrinsically disordered proteins
The abundance of intrinsic disorder in the protein realm and its role in a variety of
physiological and pathological cellular events have strengthened the interest of the scientific …
physiological and pathological cellular events have strengthened the interest of the scientific …
Self-assembling peptides: Structure, function, in silico prediction and applications
A Vahedifar, J Wu - Trends in Food Science & Technology, 2022 - Elsevier
Background Food proteins are natural sources of self-assembling peptides (SAPs) which
could form self-assembled nanostructures, including definite (eg, fibrils and nanotubes) and …
could form self-assembled nanostructures, including definite (eg, fibrils and nanotubes) and …
CPAD 2.0: a repository of curated experimental data on aggregating proteins and peptides
Abstract The Curated Protein Aggregation Database (CPAD) is a manually curated and
open-access database dedicated to providing comprehensive information related to …
open-access database dedicated to providing comprehensive information related to …
[HTML][HTML] Aggregating amyloid resources: A comprehensive review of databases on amyloid-like aggregation
Protein aggregation is responsible for several degenerative conditions in humans, and it is
also a bottleneck in industrial protein production and storage of biotherapeutics …
also a bottleneck in industrial protein production and storage of biotherapeutics …
Prediction of protein aggregation propensity via Data-Driven approaches
Protein aggregation occurs when misfolded or unfolded proteins physically bind together
and can promote the development of various amyloid diseases. This study aimed to …
and can promote the development of various amyloid diseases. This study aimed to …
AmyCo: the amyloidoses collection
Amyloid fibrils are formed when soluble proteins misfold into highly ordered insoluble
fibrillar aggregates and affect various organs and tissues. The deposition of amyloid fibrils is …
fibrillar aggregates and affect various organs and tissues. The deposition of amyloid fibrils is …
Sequence-and structure-based prediction of amyloidogenic regions in proteins
H Bouziane, A Chouarfia - Soft Computing, 2020 - Springer
Abstract Machine learning methods are increasingly used in proteomics research, especially
in analyzing and predicting protein structures, functions, subcellular localizations and …
in analyzing and predicting protein structures, functions, subcellular localizations and …
Crowder induced structural modulation of a multi-domain protein during its early stages of aggregation: A FRET-based and protein solvation study
Protein aggregation has been known for long to be the prime cause for several neurological
disorders in human beings. While protein aggregation is itself a complex process …
disorders in human beings. While protein aggregation is itself a complex process …
Prediction of protein aggregation.
K Khalili, F Farzam, B Dabirmanesh… - Progress in Molecular …, 2024 - europepmc.org
The scientific community is very interested in protein aggregation because of its involvement
in several neurodegenerative diseases and its significance in industry. Remarkably, fibrillar …
in several neurodegenerative diseases and its significance in industry. Remarkably, fibrillar …