[HTML][HTML] A systematic review and meta-analysis of somatic and germline DNA sequence biomarkers of esophageal cancer survival, therapy response and stage

JM Findlay, MR Middleton, I Tomlinson - Annals of Oncology, 2015 - Elsevier
Recent advances in next generation sequencing reinforce the potential for DNA sequence
markers to guide esophageal cancer management. We report the first systematic review and …

Genetic variation in the DNA repair pathway as a potential determinant of response to platinum‐based chemotherapy in breast cancer

F Beheshti, SM Hassanian, M Khazaei… - Journal of cellular …, 2018 - Wiley Online Library
Platinum‐based chemotherapy is often used as a first‐line treatment for patient with breast
cancer. Platinum agents bind to DNA, forming adducts that contain intra and inter‐strand …

Promoter polymorphisms of TOP2A and ERCC1 genes as predictive factors for chemotherapy in non‐small cell lung cancer patients

A Grenda, J Błach, M Szczyrek, P Krawczyk… - Cancer …, 2020 - Wiley Online Library
Abstract Background Topoisomerase 2‐alpha (TOP2A) is an enzyme that controls topologic
changes in DNA during transcription and replication. ERCC1 is an enzyme that takes part in …

[PDF][PDF] ERCC2 Lys751Gln rs13181 and XRCC2 Arg188His rs3218536 gene polymorphisms contribute to susceptibility of colon, gastric, liver, lung and prostate cancer

E Balkan, M Bilici, B Gundogdu, N Aksungur… - Journal Of …, 2020 - academia.edu
Purpose: Cancer is the leading cause of death in economically developed countries and the
second leading cause of death in developing countries. The relationship between genetic …

Effects of IGF2BP2, KCNQ1 and GCKR Polymorphisms on Clinical Outcome in Metastatic Gastric Cancer Treated with EOF Regimen

X Liu, Z Chen, X Zhao, M Huang, C Wang… - …, 2015 - Taylor & Francis
Aim: The present study analyzed Type 2 diabetes mellitus (T2D)-related gene
polymorphisms and their impacts on chemotherapeutic response and survival in patients …

Association between the ERCC1 rs11615 polymorphism and clinical outcomes of oxaliplatin-based chemotherapies in gastrointestinal cancer: a meta-analysis

SC Ma, Y Zhao, T Zhang, XL Ling… - OncoTargets and …, 2015 - Taylor & Francis
Purpose The relationship between the excision repair cross-complementing 1 (ERCC1)
rs11615 polymorphism (C/T) and responses to oxaliplatin-based chemotherapy for gastric …

Association of single nucleotide polymorphisms of ERCC1 and XPF with colorectal cancer risk and interaction with tobacco use

R Hou, Y Liu, YE Feng, L Sun, Z Shu, J Zhao, S Yang - Gene, 2014 - Elsevier
We investigated the association between polymorphisms in excision repair cross-
complementation group 1 (ERCC1)(rs3212986, rs2298881 and rs11615) and xeroderma …

[HTML][HTML] Effect of ERCC2 rs13181 and rs1799793 polymorphisms and environmental factors on the prognosis of patients with lung cancer

H Zhang, Y Li, S Guo, Y Wang, H Wang… - American journal of …, 2020 - ncbi.nlm.nih.gov
Purpose: The 5-year survival rate of patients with lung cancer in China is< 20%, and
predicting their prognosis is difficult. Here, we investigated the association between two …

Methods and significance of the combined detection of HER2 gene amplification and chemosensitivity in gastric cancer

YK Wang, SN Wang, YY Li, GP Wang, T Yun… - Cancer …, 2018 - content.iospress.com
OBJECTIVE: This study aims to investigate the significance of combined detection of HER2
gene amplification and chemosensitivity in gastric cancer. METHODS …

[PDF][PDF] Effect of ERCC1 polymorphism on the response to chemotherapy and clinical outcome of non-small cell lung cancer

H Gao, RC Ge, HY Liu, Y Wang, S Yan - Genet Mol Res, 2014 - funpecrp.com.br
We conducted a cohort study to investigate the role of 3 single-nucleotide polymorphisms of
the excision repair crosscomplementation group 1 (ERCC1) gene on the response to …