Introduction to Fission Yeast as a Model System Cold Spring Harbor Protocols Skip to main
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Meiotic progression requires precise orchestration, such that one round of DNA replication is
followed by two meiotic divisions. The order and timing of meiotic events is controlled …

Faithful genome propagation requires coordination between nuclear envelope (NE)
breakdown, spindle formation, and chromosomal events. The conserved linker of …

Advanced techniques including the chromosome conformation capture (3C) methodology
and its derivatives are complementing microscopy approaches to study genome …

The role of the conserved meiotic telomere bouquet has been enigmatic for over a century.
We showed previously that disruption of the fission yeast bouquet impairs spindle formation …

Telomeres and centromeres have traditionally been considered to perform distinct roles.
During meiotic prophase, in a conserved chromosomal configuration called the bouquet …

Pairing of homologous chromosomes is a crucial step in meiosis, which in fission yeast
depends on nuclear oscillations. However, how nuclear oscillations help pairing is …

Telomeres protect chromosome ends and are distinguished from DNA double-strand breaks
(DSBs) by means of a specialized chromatin composed of DNA repeats bound by a …

During meiotic prophase, chromosome arrangement and oscillation promote the pairing of
homologous chromosomes for meiotic recombination. This dramatic movement involves …

The processes of DNA replication and mitosis allow the genetic information of a cell to be
copied and transferred reliably to its daughter cells. However, if DNA replication and cell …