Genistein: an integrative overview of its mode of action, pharmacological properties, and health benefits

J Sharifi-Rad, C Quispe, M Imran, A Rauf… - Oxidative medicine …, 2021 - Wiley Online Library
Genistein is an isoflavone first isolated from the brooming plant Dyer's Genista tinctoria L.
and is widely distributed in the Fabaceae family. As an isoflavone, mammalian genistein …

Polyphenol uses in biomaterials engineering

A Shavandi, AEDA Bekhit, P Saeedi, Z Izadifar… - Biomaterials, 2018 - Elsevier
Polyphenols are micronutrients obtained from diet that have been suggested to play an
important role in health. The health benefits of polyphenols and their protective effects in …

Understanding the composition, biosynthesis, accumulation and transport of flavonoids in crops for the promotion of crops as healthy sources of flavonoids for human …

YS Ku, MS Ng, SS Cheng, AWY Lo, Z Xiao, TS Shin… - Nutrients, 2020 - mdpi.com
Flavonoids are a class of polyphenolic compounds that naturally occur in plants. Sub-groups
of flavonoids include flavone, flavonol, flavanone, flavanonol, anthocyanidin, flavanol and …

Functions and action mechanisms of flavonoids genistein and icariin in regulating bone remodeling

LG Ming, KM Chen, CJ Xian - Journal of cellular physiology, 2013 - Wiley Online Library
Increasingly natural products particularly flavonoids are being explored for their therapeutic
potentials in reducing bone loss and maintaining bone health. This study has reviewed …

Icariin is more potent than genistein in promoting osteoblast differentiation and mineralization in vitro

HP Ma, LG Ming, BF Ge, YK Zhai… - Journal of cellular …, 2011 - Wiley Online Library
There has been a strong interest in searching for natural therapies for osteoporosis.
Genistein, an isoflavone abundant in soy, and icariin, a prenylated flavonol glycoside …

Quercitrin and taxifolin stimulate osteoblast differentiation in MC3T3-E1 cells and inhibit osteoclastogenesis in RAW 264.7 cells

M Satué, M del Mar Arriero, M Monjo… - Biochemical Pharmacology, 2013 - Elsevier
Flavonoids are natural antioxidants that positively influence bone metabolism. The present
study screened among different flavonoids to identify biomolecules for potential use in bone …

[HTML][HTML] Potential of natural products in osteosarcoma treatment: Focus on molecular mechanisms

M Tobeiha, A Rajabi, A Raisi, M Mohajeri… - Biomedicine & …, 2021 - Elsevier
Osteosarcoma is the most frequent type of bone cancer found in children and adolescents,
and commonly arises in the metaphyseal region of tubular long bones. Standard therapeutic …

Biodegradable polymers, current trends of research and their applications, a review

M Čolnik, M Knez-Hrnčič, M Škerget… - Chemical industry and …, 2020 - doiserbia.nb.rs
Biodegradable polymers have been developing rapidly in the last years and are widely used
today in the fields of pharmacy, clinical biomedicine, cosmetic, medical, and packing …

MATE-type proteins are responsible for isoflavone transportation and accumulation in soybean seeds

MS Ng, YS Ku, WS Yung, SS Cheng, CK Man… - International journal of …, 2021 - mdpi.com
Soybeans are nutritionally important as human food and animal feed. Apart from the
macronutrients such as proteins and oils, soybeans are also high in health-beneficial …

Genistein inhibits osteoclastic differentiation of RAW 264.7 cells via regulation of ROS production and scavenging

SH Lee, JK Kim, HD Jang - International Journal of Molecular Sciences, 2014 - mdpi.com
Genistein, a phytoestrogen, has been demonstrated to have a bone-sparing and
antiresorptive effect. Genistein can inhibit the osteoclast formation of receptor activator of …