Computational modeling of realistic cell membranes
Cell membranes contain a large variety of lipid types and are crowded with proteins,
endowing them with the plasticity needed to fulfill their key roles in cell functioning. The …
endowing them with the plasticity needed to fulfill their key roles in cell functioning. The …
Multifaceted computational modeling in glycoscience
S Perez, O Makshakova - Chemical Reviews, 2022 - ACS Publications
Glycoscience assembles all the scientific disciplines involved in studying various molecules
and macromolecules containing carbohydrates and complex glycans. Such an ensemble …
and macromolecules containing carbohydrates and complex glycans. Such an ensemble …
Characterization of lipid–protein interactions and lipid-mediated modulation of membrane protein function through molecular simulation
The cellular membrane constitutes one of the most fundamental compartments of a living
cell, where key processes such as selective transport of material and exchange of …
cell, where key processes such as selective transport of material and exchange of …
Bacterial glycosyltransferases: challenges and opportunities of a highly diverse enzyme class toward tailoring natural products
The enzyme subclass of glycosyltransferases (GTs; EC 2.4) currently comprises 97 families
as specified by CAZy classification. One of their important roles is in the biosynthesis of …
as specified by CAZy classification. One of their important roles is in the biosynthesis of …
[HTML][HTML] Microbial expression systems for membrane proteins
MV Dilworth, MS Piel, KE Bettaney, P Ma, J Luo… - Methods, 2018 - Elsevier
Despite many high-profile successes, recombinant membrane protein production remains a
technical challenge; it is still the case that many fewer membrane protein structures have …
technical challenge; it is still the case that many fewer membrane protein structures have …
Protein amphipathic helix insertion: A mechanism to induce membrane fission
One of the fundamental features of biomembranes is the ability to fuse or to separate. These
processes called respectively membrane fusion and fission are central in the homeostasis of …
processes called respectively membrane fusion and fission are central in the homeostasis of …
Extension of cell membrane boosting squalene production in the engineered Escherichia coli
Y Meng, X Shao, Y Wang, Y Li, X Zheng… - Biotechnology and …, 2020 - Wiley Online Library
Squalene is a lipophilic and non‐volatile triterpene with many industrial applications for
food, pharmaceuticals, and cosmetics. Metabolic engineering focused on optimization of the …
food, pharmaceuticals, and cosmetics. Metabolic engineering focused on optimization of the …
Curvature sensing by cardiolipin in simulated buckled membranes
Cardiolipin is a non-bilayer phospholipid with a unique dimeric structure. It localizes to
negative curvature regions in bacteria and is believed to stabilize respiratory chain …
negative curvature regions in bacteria and is believed to stabilize respiratory chain …
Anisotropic membrane curvature sensing by amphipathic peptides
Many proteins and peptides have an intrinsic capacity to sense and induce membrane
curvature, and play crucial roles for organizing and remodeling cell membranes. However …
curvature, and play crucial roles for organizing and remodeling cell membranes. However …
A vesicle-to-sponge transition via the proliferation of membrane-linking pores in ω-3 polyunsaturated fatty acid-containing lipid assemblies
We investigate the nanostructure evolution and the membrane reorganization of diluted lipid
dispersions of self-assembled monoolein (MO)/eicosapentaenoic acid (EPA, 20: 5) mixtures …
dispersions of self-assembled monoolein (MO)/eicosapentaenoic acid (EPA, 20: 5) mixtures …