Monocyte programming by cancer therapy
M Patysheva, A Frolova, I Larionova… - Frontiers in …, 2022 - frontiersin.org
Monocytes in peripheral blood circulation are the precursor of essential cells that control
tumor progression, that include tumor-associated macrophages (TAMs), dendritic cells …
tumor progression, that include tumor-associated macrophages (TAMs), dendritic cells …
Development of exhausted memory monocytes and underlying mechanisms
Pathogenic inflammation and immuno-suppression are cardinal features of exhausted
monocytes increasingly recognized in septic patients and murine models of sepsis …
monocytes increasingly recognized in septic patients and murine models of sepsis …
Simultaneous C5 and CD14 inhibition limits inflammation and organ dysfunction in pig polytrauma
L Lupu, K Horst, J Greven, Ü Mert… - Frontiers in …, 2022 - frontiersin.org
Dysfunctional complement activation and Toll-like receptor signaling immediately after
trauma are associated with development of trauma-induced coagulopathy and multiple …
trauma are associated with development of trauma-induced coagulopathy and multiple …
[HTML][HTML] Altered DNA methylation underlies monocyte dysregulation and immune exhaustion memory in sepsis
Monocytes can develop an exhausted memory state characterized by reduced
differentiation, pathogenic inflammation, and immune suppression that drives immune …
differentiation, pathogenic inflammation, and immune suppression that drives immune …
Effect of stretching on inflammation in a subcutaneous carrageenan mouse model analyzed at single‐cell resolution
L Berrueta, D Muñoz‐Vergara, D Martin… - Journal of Cellular …, 2023 - Wiley Online Library
Understanding the factors that influence the biological response to inflammation is crucial,
due to its involvement in physiological and pathological processes, including tissue …
due to its involvement in physiological and pathological processes, including tissue …
Multi-omics integration reveals only minor long-term molecular and functional sequelae in immune cells of individuals recovered from COVID-19
The majority of COVID-19 patients experience mild to moderate disease course and recover
within a few weeks. An increasing number of studies characterized the long-term changes in …
within a few weeks. An increasing number of studies characterized the long-term changes in …
Comparative analyses of monocyte memory dynamics from mice to humans
Background Innate monocytes can adopt dynamic “memory” states ranging from low-grade
inflammation to pathogenic exhaustion, dependent upon signal strength and history of …
inflammation to pathogenic exhaustion, dependent upon signal strength and history of …
Monocytes reprogrammed by 4-PBA potently contribute to the resolution of inflammation and atherosclerosis
BACKGROUND: Chronic inflammation initiated by inflammatory monocytes underlies the
pathogenesis of atherosclerosis. However, approaches that can effectively resolve chronic …
pathogenesis of atherosclerosis. However, approaches that can effectively resolve chronic …
Immune-enhancing neutrophils reprogrammed by subclinical low-dose endotoxin in cancer treatment
Y Zhang, C Lee, S Geng, J Wang, U Bohara… - EMBO Molecular …, 2024 - embopress.org
Despite the re-emergence of the pioneering “Coley's toxin” concept in anti-cancer immune
therapies highlighted by check-point inhibitors and CAR-T approaches, fundamental …
therapies highlighted by check-point inhibitors and CAR-T approaches, fundamental …
Non-Coding Transcriptome Provides Novel Insights into the Escherichia coli F17 Susceptibility of Sheep Lamb
W Chen, X Lv, W Zhang, T Hu, X Cao, Z Ren… - Biology, 2022 - mdpi.com
Simple Summary Diarrhea and vomiting caused by Escherichia coli (E. coli) F17 are
considered significant threats to animal farming. In the present study, RNA-Seq was …
considered significant threats to animal farming. In the present study, RNA-Seq was …