Improving mosquito control strategies with population genomics

TL Schmidt, NM Endersby-Harshman… - Trends in Parasitology, 2021 - cell.com
Mosquito control strategies increasingly apply knowledge from population genomics
research. This review highlights recent applications to three research domains: mosquito …

Abundance of conserved CRISPR-Cas9 target sites within the highly polymorphic genomes of Anopheles and Aedes mosquitoes

H Schmidt, TC Collier, MJ Hanemaaijer… - Nature …, 2020 - nature.com
A number of recent papers report that standing genetic variation in natural populations
includes ubiquitous polymorphisms within target sites for Cas9-based gene drive (CGD) and …

Resolving confusion in the native distribution of Aedes (Hulecoeteomyia) koreicus (Diptera: Culicidae)

S Seok, M Mogi, Y Lee - Journal of Medical Entomology, 2024 - academic.oup.com
Recent studies on invasive Aedes koreicus (Edwards 1917) have been conducted to
elucidate the source population introduced to Europe. However, current information about …

Chromosome-level genome assemblies of the malaria vectors Anopheles coluzzii and Anopheles arabiensis

A Zamyatin, P Avdeyev, J Liang, A Sharma… - …, 2021 - academic.oup.com
Abstract Background Anopheles coluzzii and Anopheles arabiensis belong to the
Anopheles gambiae complex and are among the major malaria vectors in sub-Saharan …

Selection of sites for field trials of genetically engineered mosquitoes with gene drive

GC Lanzaro, M Campos, M Crepeau… - Evolutionary …, 2021 - Wiley Online Library
Novel malaria control strategies using genetically engineered mosquitoes (GEMs) are on
the horizon. Population modification is one approach wherein mosquitoes are engineered …

Mosquito tagging using DNA-barcoded nanoporous protein microcrystals

JD Stuart, DA Hartman, LI Gray, AA Jones… - PNAS …, 2022 - academic.oup.com
Conventional mosquito marking technology for mark–release–recapture (MRR) is quite
limited in terms of information capacity and efficacy. To overcome both challenges, we have …

Anopheles gambiae on remote islands in the Indian Ocean: origins and prospects for malaria elimination by genetic modification of extant populations

RE Ditter, M Campos, MW Crepeau, J Pinto… - Scientific Reports, 2023 - nature.com
The mosquito Anopheles gambiae ss is a primary malaria vector throughout sub-Saharan
Africa including the islands of the Comoros archipelago (Anjouan, Grande Comore, Mayotte …

On species delimitation, hybridization and population structure of cassava whitefly in Africa

S Elfekih, WT Tay, A Polaszek, KHJ Gordon, D Kunz… - Scientific Reports, 2021 - nature.com
The Bemisia cassava whitefly complex includes species that cause severe crop damage
through vectoring cassava viruses in eastern Africa. Currently, this whitefly complex is …

The origin of island populations of the African malaria mosquito, Anopheles coluzzii

M Campos, M Hanemaaijer, H Gripkey… - Communications …, 2021 - nature.com
Anopheles coluzzii is a major malaria vector throughout its distribution in west-central Africa.
Here we present a whole-genome study of 142 specimens from nine countries in continental …

CRISPR-Cas9 and Cas12a target site richness reflects genomic diversity in natural populations of Anopheles gambiae and Aedes aegypti mosquitoes

TC Collier, Y Lee, DK Mathias, VL Del Amo - BMC genomics, 2024 - Springer
Due to limitations in conventional disease vector control strategies including the rise of
insecticide resistance in natural populations of mosquitoes, genetic control strategies using …