The Characteristic of Virulence, Biofilm and Antibiotic Resistance of Klebsiella pneumoniae

G Wang, G Zhao, X Chao, L Xie, H Wang - International journal of …, 2020 - mdpi.com
Klebsiella pneumoniae is an important gram-negative opportunistic pathogen that causes a
variety of infectious diseases, including urinary tract infections, bacteremia, pneumonia, and …

Population genomics of Klebsiella pneumoniae

KL Wyres, MMC Lam, KE Holt - Nature Reviews Microbiology, 2020 - nature.com
Klebsiella pneumoniae is a common cause of antimicrobial-resistant opportunistic infections
in hospitalized patients. The species is naturally resistant to penicillins, and members of the …

A genomic surveillance framework and genotyping tool for Klebsiella pneumoniae and its related species complex

MMC Lam, RR Wick, SC Watts, LT Cerdeira… - Nature …, 2021 - nature.com
Klebsiella pneumoniae is a leading cause of antimicrobial-resistant (AMR) healthcare-
associated infections, neonatal sepsis and community-acquired liver abscess, and is …

Clinical outcomes and bacterial characteristics of carbapenem-resistant Klebsiella pneumoniae complex among patients from different global regions (CRACKLE-2): a …

M Wang, M Earley, L Chen, BM Hanson… - The Lancet Infectious …, 2022 - thelancet.com
Summary Background Carbapenem-resistant Klebsiella pneumoniae (CRKP) is a global
threat. We therefore analysed the bacterial characteristics of CRKP infections and the …

Genomic dissection of Klebsiella pneumoniae infections in hospital patients reveals insights into an opportunistic pathogen

CL Gorrie, M Mirčeta, RR Wick, LM Judd… - Nature …, 2022 - nature.com
Klebsiella pneumoniae is a major cause of opportunistic healthcare-associated infections,
which are increasingly complicated by the presence of extended-spectrum beta-lactamases …

Colonization, Infection, and the Accessory Genome of Klebsiella pneumoniae

RM Martin, MA Bachman - Frontiers in cellular and infection …, 2018 - frontiersin.org
Klebsiella pneumoniae is a Gram-negative pathogen that has a large accessory genome of
plasmids and chromosomal gene loci. This accessory genome divides K. pneumoniae …

Pathogenesis of gram-negative bacteremia

CL Holmes, MT Anderson, HLT Mobley… - Clinical microbiology …, 2021 - Am Soc Microbiol
Gram-negative bacteremia is a devastating public health threat, with high mortality in
vulnerable populations and significant costs to the global economy. Concerningly, rates of …

[HTML][HTML] A global perspective on the convergence of hypervirulence and carbapenem resistance in Klebsiella pneumoniae

P Lan, Y Jiang, J Zhou, Y Yu - Journal of global antimicrobial resistance, 2021 - Elsevier
Hypervirulence and carbapenem resistance have emerged as two distinct evolutionary
directions for Klebsiella pneumoniae, which pose a great threat in clinical settings. Multiple …

A fatal outbreak of ST11 carbapenem-resistant hypervirulent Klebsiella pneumoniae in a Chinese hospital: a molecular epidemiological study

D Gu, N Dong, Z Zheng, D Lin, M Huang… - The Lancet infectious …, 2018 - thelancet.com
Summary Background Hypervirulent Klebsiella pneumoniae strains often cause life-
threatening community-acquired infections in young and healthy hosts, but are usually …

GrapeTree: visualization of core genomic relationships among 100,000 bacterial pathogens

Z Zhou, NF Alikhan, MJ Sergeant, N Luhmann… - Genome …, 2018 - genome.cshlp.org
Current methods struggle to reconstruct and visualize the genomic relationships of large
numbers of bacterial genomes. GrapeTree facilitates the analyses of large numbers of allelic …