NORAD, a critical long non-coding RNA in human cancers

N Soghli, T Yousefi, M Abolghasemi, D Qujeq - Life Sciences, 2021 - Elsevier
The incidence of cancer is growing worldwide, and it is becoming the most common cause
of death. Long non-coding RNAs (lncRNAs) are a group of RNA transcripts with a length …

Current status and future perspective on molecular imaging and treatment of neuroblastoma

L Feng, S Li, C Wang, J Yang - Seminars in Nuclear Medicine, 2023 - Elsevier
Neuroblastoma is the most common extracranial solid tumor in children and arises from
anywhere along the sympathetic nervous system. It is a highly heterogeneous disease with …

SP1-induced lncRNA DUBR promotes stemness and oxaliplatin resistance of hepatocellular carcinoma via E2F1-CIP2A feedback

S Liu, XY Bu, A Kan, L Luo, YJ Xu, HL Chen, X Lin… - Cancer Letters, 2022 - Elsevier
Oxaliplatin-based chemotherapy is widely used to treat advanced hepatocellular carcinoma
(HCC), but many patients develop drug resistance that leads to tumor recurrence. Cancer …

NEAT1 polyA-modulating antisense oligonucleotides reveal opposing functions for both long non-coding RNA isoforms in neuroblastoma

A Naveed, JA Cooper, R Li, A Hubbard, J Chen… - Cellular and Molecular …, 2021 - Springer
Many long non-coding RNAs (lncRNA) are highly dysregulated in cancer and are emerging
as therapeutic targets. One example is NEAT1, which consists of two overlapping lncRNA …

N6-methyladenosine-mediated SH3BP5-AS1 upregulation promotes GEM chemoresistance in pancreatic cancer by activating the Wnt signaling pathway

C Lin, Y Wang, Y Dong, S Lai, L Wang, S Weng… - Biology Direct, 2022 - Springer
Background Pancreatic cancer (PC) is highly malignant. Chemotherapy is the main
treatment strategy, especially for patients with advanced PC. However, chemoresistance has …

[HTML][HTML] LncRNA NORAD accelerates the progression and doxorubicin resistance of neuroblastoma through up-regulating HDAC8 via sponging miR-144-3p

B Wang, L Xu, J Zhang, X Cheng, Q Xu, J Wang… - Biomedicine & …, 2020 - Elsevier
The dysregulation of non-coding RNAs (ncRNAs) often caused aberrant cell behaviors. In
the present study, we focused on the role of long noncoding RNA (lncRNA) non-coding RNA …

LncRNA DHRS4-AS1 ameliorates hepatocellular carcinoma by suppressing proliferation and promoting apoptosis via miR-522-3p/SOCS5 axis

Y Zhou, K Li, X Zou, Z Hua, H Wang, W Bian… - …, 2021 - Taylor & Francis
Recent years have seen much effect in revealing the pathological association between
lncRNA and HCC. Herein, we identified lncRNA DHRS4-AS1 as a potential tumor …

LncRNA DHRS4-AS1 inhibits the stemness of NSCLC cells by sponging miR-224-3p and upregulating TP53 and TET1

F Yan, W Zhao, X Xu, C Li, X Li, S Liu, L Shi… - Frontiers in cell and …, 2020 - frontiersin.org
Non-small cell lung cancer (NSCLC) is the leading cause of cancer-related death. This study
aimed to examine the roles of DHRS4-AS1/miR-224-3p signaling in the cancer cell …

Biomarkers in neuroblastoma: an insight into their potential diagnostic and prognostic utilities

F Shawraba, H Hammoud, Y Mrad, Z Saker… - … Treatment Options in …, 2021 - Springer
Opinion Statement Neuroblastoma (NB) is a heterogeneous solid tumor of the pediatric
population that originates from neural crest cells and affects the developing sympathetic …

Integrated analysis of cancer tissue and vitreous humor from retinoblastoma eyes reveals unique tumor-specific metabolic and cellular pathways in advanced and non …

VS Babu, A Mallipatna, D Sa, G Dudeja, R Kannan… - Cells, 2022 - mdpi.com
Retinoblastoma (Rb) is a pediatric intraocular malignancy that is proposed to originate from
maturing cone cell precursors in the developing retina. The molecular mechanisms …