The immune contexture and Immunoscore in cancer prognosis and therapeutic efficacy

D Bruni, HK Angell, J Galon - Nature Reviews Cancer, 2020 - nature.com
Abstract The international American Joint Committee on Cancer/Union for International
Cancer Control (AJCC/UICC) tumour-node-metastasis (TNM) staging system provides the …

Adipose tissue in obesity‐related inflammation and insulin resistance: cells, cytokines, and chemokines

K Makki, P Froguel, I Wolowczuk - … Scholarly Research Notices, 2013 - Wiley Online Library
Adipose tissue is a complex organ that comprises a wide range of cell types with diverse
energy storage, metabolic regulation, and neuroendocrine and immune functions. Because …

Myeloid-derived suppressor cells: not only in tumor immunity

G Pawelec, CP Verschoor… - Frontiers in …, 2019 - frontiersin.org
Since the realization that immature myeloid cells are powerful modulators of the immune
response, many studies on “myeloid-derived suppressor cells”(MDSCs) have documented …

Trial watch: Prognostic and predictive value of the immune infiltrate in cancer

L Senovilla, E Vacchelli, J Galon, S Adjemian… - …, 2012 - Taylor & Francis
Solid tumors are constituted of a variety of cellular components, including bona fide
malignant cells as well as endothelial, structural and immune cells. On one hand, the tumor …

On the armament and appearances of human myeloid-derived suppressor cells

I Poschke, R Kiessling - Clinical immunology, 2012 - Elsevier
Myeloid-derived suppressor cells (MDSC) have frequently been observed in patients with
cancer. This heterogeneous population of myeloid cells can exert potent suppression of …

[HTML][HTML] Monocytic myeloid-derived suppressor cells accumulate in renal transplant patients and mediate CD4+ Foxp3+ Treg expansion

Y Luan, E Mosheir, MC Menon, D Wilson… - American journal of …, 2013 - Elsevier
Myeloid-derived suppressor cells (MDSC) are negative regulators of the immune response
and are in part responsible for the inhibition of the T cell–mediated immune responses …

Myeloid-derived suppressor cells in transplantation: the dawn of cell therapy

W Zhang, J Li, G Qi, G Tu, C Yang, M Xu - Journal of translational …, 2018 - Springer
Myeloid-derived suppressor cells (MDSCs) are a series of innate cells that play a significant
role in inhibiting T cell-related responses. This heterogeneous population of immature cells …

Myeloid-derived suppressor cells and their potential application in transplantation

JR Scalea, YS Lee, E Davila, JS Bromberg - Transplantation, 2018 - journals.lww.com
Myeloid-derived suppressor cells (MDSCs) are a heterogeneous population of
immunosuppressive cells of the myeloid lineage upregulated by mediators of inflammation …

Aging affects the role of myeloid-derived suppressor cells in alloimmunity

A Schroeter, MJ Roesel, T Matsunaga, Y Xiao… - Frontiers in …, 2022 - frontiersin.org
Myeloid-derived suppressor cells (MDSC) are defined as a group of myeloid cells with
potent immunoregulatory functions that have been shown to be involved in a variety of …

[HTML][HTML] SIRPα/CD47 axis controls the maintenance of transplant tolerance sustained by myeloid-derived suppressor cells

S Pengam, J Durand, C Usal, V Gauttier, N Dilek… - American Journal of …, 2019 - Elsevier
Myeloid-derived suppressor cells (MDSC) are a heterogeneous population of immature
hematopoietic precursors known to suppress immune responses. Interaction of SIRP alpha …