Remdesivir: a review in COVID-19

HA Blair - Drugs, 2023 - Springer
Remdesivir (Veklury®), a nucleotide analogue prodrug with broad-spectrum antiviral activity,
is approved for the treatment of coronavirus disease 2019 (COVID-19), the illness caused by …

Corticosteroids in COVID-19: pros and cons

A Bahsoun, Y Fakih, R Zareef, F Bitar, M Arabi - Frontiers in Medicine, 2023 - frontiersin.org
The wide and rapid spread of the COVID-19 pandemic has placed an unanticipated burden
on the global healthcare sector. This necessitated a swift response from the international …

Formulation and in vitro characterization of nanoemulsions containing remdesivir or licorice extract: A potential subcutaneous injection for coronavirus treatment

G Al Zahraa, GF Balata - Colloids and Surfaces B: Biointerfaces, 2024 - Elsevier
The management of coronavirus necessitates that medicines are available, reasonably
priced, and easy to administer. The work aimed at formulating and characterizing remdesivir …

Remdesivir Use in the Real-World Setting: An Overview of Available Evidence

K Akinosoglou, EA Rigopoulos, G Schinas, G Kaiafa… - Viruses, 2023 - mdpi.com
In the years of Coronavirus Disease 2019 (COVID-19), various treatment options have been
utilized. COVID-19 continues to circulate in the global population, and the evolution of the …

Clinical evolution and mortality of critically ill patients with SARS-CoV-2 pneumonia treated with remdesivir in an adult intensive care unit of Paraguay

J Figueredo, LF Lopez, BF Leguizamon… - BMC Infectious …, 2024 - Springer
Background The health crisis due to Covid-19 led to the search for therapeutics that could
improve the evolution of the disease. Remdesivir, an antiviral that interferes with viral …

Nirmatrelvir/ritonavir treatment in SARS-CoV-2 positive kidney transplant recipients–a case series with four patients

J Schneider, R Wobser, W Kühn, D Wagner, Y Tanriver… - BMC nephrology, 2023 - Springer
Background Despite vaccination coronavirus disease 2019 (COVID-19)-associated mortality
caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) remains high in …

[HTML][HTML] Longitudinal Study of SARS-CoV-2 Vaccinations and Infections in Patients with Gastrointestinal Cancer: Stabilizing Immune Responses and Neutralizing …

MA Gonzalez-Carmona, AM Schmitz, M Berger… - International Journal of …, 2024 - mdpi.com
This longitudinal study examined how active gastrointestinal (GI) cancer types affect immune
responses to SARS-CoV-2, focusing on the ability to neutralize the Omicron variants …

Methylene blue for COVID-19 ARDS: insights from a randomized Clinical Trial

ZS Sanei, F Shahrahmani, B Khaleghi Manesh… - Naunyn-Schmiedeberg's …, 2024 - Springer
Background Around the world, the COVID-19 pandemic has presented many difficulties, and
acute respiratory distress syndrome (ARDS) has become a major worry. The antiviral and …

Antiviral treatment of COVID-19: which role can clinical parameters play in therapy evaluation?

YR Hübner, N Spuck, M Berger, S Schlabe, GJ Rieke… - Infection, 2023 - Springer
With great interest, we read the article “Use and Effectiveness of Remdesivir for the
Treatment of Patients with COVID-19 Using Data from the Lean European Open Survey on …

A fatal course of COVID-19 during the Omicron surge: can you estimate your patients' SARS-CoV-2 immune status?

M Mersch, S Schlabe, S Breitschwerdt, J Laufenberg… - Infection, 2024 - Springer
We present a case of an ultimately fatal course of COVID-19 (coronavirus disease-19) in an
81-year-old female patient during the Omicron surge. The patient did not represent the …