Role of human milk bioactives on infants' gut and immune health

LE Carr, MD Virmani, F Rosa, D Munblit… - Frontiers in …, 2021 - frontiersin.org
Exclusive human milk feeding of the newborn is recommended during the first 6 months of
life to promote optimal health outcomes during early life and beyond. Human milk contains a …

[HTML][HTML] Fates of CD8+ T cells in tumor microenvironment

NR Maimela, S Liu, Y Zhang - Computational and structural biotechnology …, 2019 - Elsevier
Studies have reported a positive correlation between elevated CD8+ T cells in the tumor
microenvironment (TME) and good prognosis in cancer. However, the mechanisms linking T …

MicroRNA let-7 and viral infections: focus on mechanisms of action

A Letafati, S Najafi, M Mottahedi, M Karimzadeh… - Cellular & Molecular …, 2022 - Springer
MicroRNAs (miRNAs) are fundamental post-transcriptional modulators of several critical
cellular processes, a number of which are involved in host defense mechanisms. In …

Human breast milk: from food to active immune response with disease protection in infants and mothers

GAG Lokossou, L Kouakanou, A Schumacher… - Frontiers in …, 2022 - frontiersin.org
Breastfeeding is associated with long-term wellbeing including low risks of infectious
diseases and non-communicable diseases such as asthma, cancer, autoimmune diseases …

The roles of the Let-7 family of MicroRNAs in the regulation of cancer stemness

Y Ma, N Shen, MS Wicha, M Luo - Cells, 2021 - mdpi.com
Cancer has long been viewed as a disease of normal development gone awry. Cancer stem-
like cells (CSCs), also termed as tumor-initiating cells (TICs), are increasingly recognized as …

Let-7 enhances murine anti-tumor CD8 T cell responses by promoting memory and antagonizing terminal differentiation

AC Wells, KA Hioki, CC Angelou, AC Lynch… - Nature …, 2023 - nature.com
The success of the CD8 T cell-mediated immune response against infections and tumors
depends on the formation of a long-lived memory pool, and the protection of effector cells …

Role of MicroRNAs in Parkinson's disease

SY Goh, YX Chao, ST Dheen, EK Tan… - International journal of …, 2019 - mdpi.com
Parkinson's disease (PD) is a disabling neurodegenerative disease that manifests with
resting tremor, bradykinesia, rigidity and postural instability. Since the discovery of …

Neonatal T cells: a reinterpretation

BD Rudd - Annual review of immunology, 2020 - annualreviews.org
Neonatal CD4+ and CD8+ T cells have historically been characterized as immature or
defective. However, recent studies prompt a reinterpretation of the functions of neonatal T …

Granzyme B nanoreporter for early monitoring of tumor response to immunotherapy

A Nguyen, A Ramesh, S Kumar, D Nandi… - Science …, 2020 - science.org
Despite recent advancements in cancer immunotherapy, accurate monitoring of its efficacy
is challenging due to heterogeneous immune responses. Conventional imaging techniques …

SARS CoV-2 spike protein-guided exosome isolation facilitates detection of potential miRNA biomarkers in COVID-19 infections

S Mimmi, AM Zimbo, S Rotundo, E Cione… - Clinical Chemistry and …, 2023 - degruyter.com
Objectives Nearly three years into the pandemic, SARS-CoV-2 infections are occurring in
vaccinated and naturally infected populations. While humoral and cellular responses in …