The two major autoimmune thyroid diseases (ATDs) include Graves′ disease (GD) and
autoimmune thyroiditis (AT); both of which are characterized by infiltration of the thyroid by T …

Integrin αvβ3 is generously expressed by cancer cells and rapidly dividing endothelial cells.
The principal ligands of the integrin are extracellular matrix proteins, but we have described …

Resistance to thyroid hormone syndrome (RTH) is an autosomal dominant or recessive
genetic disease caused by mutation of either the thyroid hormone receptorβ (THR-β) gene …

Graves' disease (GD) is the most common cause of hyperthyroidism in children. A common
GD symptom is a goiter. The usual biochemical profile in children with GD is a decreased …

The enormous advances in nanomedicine and precision medicine in the past two decades
necessitated this comprehensive reference, which can be relied upon by researchers …

Background: An increased or normal serum TSH concentration, despite elevated thyroid
hormone levels, is observed in resistance to thyroid hormone (RTH) and TSH-secreting …

The hypothesis set forth is that the basis for a great many chronic debilitating conditions that
involve almost all of the physiologic systems of the body may have as the underlying cause …

Hormone resistance is defined as a reduced or absence of target tissues responsiveness to
a hormone, where the presentation is related to either a relative lack or excess of hormones …

Background: Resistance to thyroid hormone (RTH) is a rare disorder in which an
abnormality in the binding domain of the thyroid hormone receptor results in end-organ …

Background: Thyroid hormone resistance syndrome (THRS) is a rare disorder with
increased concentrations of free thyroxine (FT4) and triiodothyronine (FT3), but normal or …