Epidemiology and treatment of multidrug-resistant and extensively drug-resistant Pseudomonas aeruginosa infections

JP Horcajada, M Montero, A Oliver, L Sorlí… - Clinical microbiology …, 2019 - Am Soc Microbiol
In recent years, the worldwide spread of the so-called high-risk clones of multidrug-resistant
or extensively drug-resistant (MDR/XDR) Pseudomonas aeruginosa has become a public …

Gram-negative antibiotic resistance: there is a price to pay

TG Slama - Critical Care, 2008 - Springer
Resistance rates are increasing among several problematic Gram-negative pathogens that
are often responsible for serious nosocomial infections, including Acinetobacter spp …

ACVIM consensus statement on therapeutic antimicrobial use in animals and antimicrobial resistance

JS Weese, S Giguère, L Guardabassi… - Journal of Veterinary …, 2015 - Wiley Online Library
The epidemic of antimicrobial resistant infections continues to challenge, compromising
animal care, complicating food animal production and posing zoonotic disease risks. While …

Characteristics and determinants of outcome of hospital-acquired bloodstream infections in intensive care units: the EUROBACT International Cohort Study

A Tabah, D Koulenti, K Laupland, B Misset… - Intensive care …, 2012 - Springer
Purpose The recent increase in drug-resistant micro-organisms complicates the
management of hospital-acquired bloodstream infections (HA-BSIs). We investigated the …

Integrating rapid diagnostics and antimicrobial stewardship improves outcomes in patients with antibiotic-resistant Gram-negative bacteremia

KK Perez, RJ Olsen, WL Musick, PL Cernoch… - Journal of Infection, 2014 - Elsevier
Summary Background An intervention for Gram-negative bloodstream infections that
integrated mass spectrometry technology for rapid diagnosis with antimicrobial stewardship …

Bloodstream infections caused by antibiotic-resistant gram-negative bacilli: risk factors for mortality and impact of inappropriate initial antimicrobial therapy on outcome

CI Kang, SH Kim, WB Park, KD Lee… - Antimicrobial agents …, 2005 - Am Soc Microbiol
The marked increase in the incidence of infections due to antibiotic-resistant gram-negative
bacilli in recent years is of great concern, as patients infected by those isolates might initially …

Outcomes Analysis of Delayed Antibiotic Treatment for Hospital-Acquired Staphylococcus aureus Bacteremia

TP Lodise, PS McKinnon, L Swiderski… - Clinical infectious …, 2003 - academic.oup.com
The objective of this study was to determine the effect of delayed therapy on morbidity and
mortality associated with nosocomial Staphylococcus aureus bacteremia. The study …

Predictors of Mortality in Patients with Bloodstream Infections Caused by Extended-Spectrum-β-Lactamase-Producing Enterobacteriaceae: Importance of Inadequate …

M Tumbarello, M Sanguinetti, E Montuori… - Antimicrobial agents …, 2007 - Am Soc Microbiol
Bloodstream infections (BSI) caused by extended-spectrum β-lactamase (ESBL)-producing
organisms markedly increase the rates of treatment failure and death. We conducted a …

Nosocomial bloodstream infections in Brazilian hospitals: analysis of 2,563 cases from a prospective nationwide surveillance study

AR Marra, LFA Camargo, ACC Pignatari… - Journal of clinical …, 2011 - Am Soc Microbiol
Nosocomial bloodstream infections (nBSIs) are an important cause of morbidity and
mortality. Data from a nationwide, concurrent surveillance study, Brazilian SCOPE …

Clinical and economic outcomes in critically ill patients with nosocomial catheter-related bloodstream infections

SI Blot, P Depuydt, L Annemans… - Clinical Infectious …, 2005 - academic.oup.com
Background. Central venous catheters are universally used during the treatment of critically
ill patients. Their use, however, is associated with a substantial infection risk, potentially …