Extracellular matrix (ECM) plays a pivotal and dynamic role in the construction of tumor
microenvironment (TME), becoming the focus in cancer research and treatment. Multiple cell …

Multidrug resistance (MDR) poses a significant obstacle to effective cancer treatment, and
the tumor microenvironment (TME) is crucial for MDR development and reversal. The TME …

Lung cancer is the leading cause of cancer-related death worldwide. KRAS mutations are
the most common oncogenic alterations found in lung cancer. Unfortunately, treating KRAS …

HDAC inhibitors, which can inhibit the activity of HDAC enzymes, have been extensively
studied in tumor immunotherapy and have shown potential therapeutic effects in cancer …

Simple Summary Cancer remains a major killer of the human population. Current cancer
diagnostic and therapeutic methods are associated with shortcomings of limited targetability …

Biofabrication techniques enable the performance of bioinspired three‐dimensional (3D)
matrices resembling primary tumors. To validate their reliability, embedded cells may …

Abstract Cyclin-dependent kinase 4 (CDK4) and CDK6 inhibitors (CDK4/6i) have rapidly
received Food and Drug Administration (FDA) approval as a new type of therapy for patients …

Nanomedicine in oncology has not had the success in clinical impact that was anticipated in
the early stages of the field's development. Ideally, nanomedicines selectively accumulate in …

Purpose We report an innovative green nanotechnology utilizing an electron-rich cocktail of
phytochemicals from Yucca filamentosa L. to synthesize biocompatible gold nanoparticles …

Hepatocellular carcinoma (HCC) is a solid tumor prone to chemotherapy resistance, and
combined immunotherapy is expected to bring a breakthrough in HCC treatment. However …