Carica papaya, commonly referred to as papaya, is a member of the Caricaceae family,
boasting a diverse array of compounds and biomolecules, notably papain, with significant …

In the search for compounds that inhibit the SARS‐CoV‐2 after the onset of the COVID‐19
pandemic, isoquinoline‐containing alkaloids have been identified as compounds with high …

In this paper, an environmentally benign, convenient, and efficient one-pot three-component
reaction has been developed for the regioselective synthesis of novel 5-aroyl (or …

The COVID-19 pandemic is caused by SARS-CoV-2, an RNA virus with high transmissibility
and mutation rate. Given the paucity of orally bioavailable antiviral drugs to combat SARS …

The appearance of several coronavirus pandemics/epidemics during the last two decades
(SARS-CoV-1 in 2002, MERS-CoV in 2012, and SARS-CoV-2 in 2019) indicates that …

P38 mitogen‐activated protein kinase (p38 MAPK) signaling pathway is closely related to
severe acute respiratory syndrome coronavirus‐2 (SARS‐CoV‐2) replication and …

Severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) was declared a global
pandemic in 2020. Having rapidly spread around the globe, with the emergence of new …

Chalcone is an interesting scaffold found in the structure of many naturally occurring
molecules. Medicinal chemists are commonly interested in designing new chalcone‐based …

Previous studies indicated that natural-based chalcones have significant inhibitory effects on
the coronavirus enzymes 3CLpro and PLpro as well as modulation of some host-based …

Berberine is a well-known phytochemical with significant antiviral activity against a wide
range of viruses. Due to having a unique backbone consisting of four interconnected rings, it …