Severe acute respiratory syndrome-related coronavirus (SARS-CoV-2), the causative agent
of coronavirus disease 2019 (COVID-19), is highly contagious and remains a major public …

Myeloid cells are key drivers of physiological responses to pathogen invasion or tissue
damage. Members of the C-type lectin receptor (CLR) family stand out among the …

The liver sinusoidal endothelial cell (LSEC) forms the fenestrated wall of the hepatic
sinusoid and functions as a control post regulating and surveying the trafficking of molecules …

Carbohydrate recognition is crucial for biological processes ranging from development to
immune system function to host–pathogen interactions. The proteins that bind glycans are …

Ubiquitous occurrence in Nature, abundant presence at strategically important places such
as the cell surface and dynamic shifts in their profile by diverse molecular switches qualifies …

Highlights•Complex glycans play multifaceted roles in interplay between virus and its
host.•Host glycans serve co-receptors or specific primary receptors for viral entry.•Viral …

New SARS‐CoV‐2 variants are continuously emerging with critical implications for therapies
or vaccinations. The 22 N‐glycan sites of Spike remain highly conserved among SARS‐CoV …

Dextran, the α-1, 6-linked glucose polymer widely used in biology and medicine, promises
new applications. Linear dextran applied as a blood plasma substitute demonstrates a high …

Carbohydrates establish the third alphabet of life. As part of cellular glycoconjugates, the
glycans generate a multitude of signals in a minimum of space. The presence of distinct …

Many interactions between microbes and their hosts are driven or influenced by glycans,
whose heterogeneous and difficult to characterize structures have led to an …