Nanoengineered immune niches for reprogramming the immunosuppressive tumor microenvironment and enhancing cancer immunotherapy

H Phuengkham, L Ren, IW Shin, YT Lim - Advanced Materials, 2019 - Wiley Online Library
Cancer immunotherapies that harness the body's immune system to combat tumors have
received extensive attention and become mainstream strategies for treating cancer. Despite …

β2 Integrins—multi-functional leukocyte receptors in health and disease

M Bednarczyk, H Stege, S Grabbe, M Bros - International journal of …, 2020 - mdpi.com
β2 integrins are heterodimeric surface receptors composed of a variable α (CD11a-CD11d)
and a constant β (CD18) subunit and are specifically expressed by leukocytes. The α …

Tumor-Associated Macrophages Recruit CCR6+ Regulatory T Cells and Promote the Development of Colorectal Cancer via Enhancing CCL20 Production in Mice

J Liu, N Zhang, Q Li, W Zhang, F Ke, Q Leng, H Wang… - PloS one, 2011 - journals.plos.org
Background Tumor-associated macrophages (TAMs) remodel the colorectal cancer (CRC)
microenvironment. Yet, findings on the role of TAMs in CRC seem to be contradictory …

Models in the research process of psoriasis

K Bocheńska, E Smolińska, M Moskot… - International journal of …, 2017 - mdpi.com
Psoriasis is an ancient, universal chronic skin disease with a significant geographical
variability, with the lowest incidence rate at the equator, increasing towards the poles …

Green Phellodendri Chinensis Cortex-based carbon dots for ameliorating imiquimod-induced psoriasis-like inflammation in mice

M Zhang, J Cheng, J Hu, J Luo, Y Zhang, F Lu… - Journal of …, 2021 - Springer
Abstract Background Carbon dots (CDs) with multifaceted advantages have provided hope
for development brand-new nanodrug for treating thorny diseases. This study developed a …

Gold nanoparticles: multifaceted roles in the management of autoimmune disorders

K Koushki, S Keshavarz Shahbaz, M Keshavarz… - Biomolecules, 2021 - mdpi.com
Gold nanoparticles (GNPs) have been recently applied for various diagnostic and
therapeutic purposes. The unique properties of these nanoparticles (NPs), such as relative …

Inhibition of NLRP3 inflammasome-mediated pyroptosis in macrophage by cycloastragenol contributes to amelioration of imiquimod-induced psoriasis-like skin …

G Deng, W Chen, P Wang, T Zhan, W Zheng… - International …, 2019 - Elsevier
Psoriasis is a common chronic inflammatory skin disease, and the infiltrated macrophages in
psoriatic skin lesions play a key role in the progression of this uncontrolled cutaneous …

[HTML][HTML] New frontiers in psoriatic disease research, part I: genetics, environmental triggers, immunology, pathophysiology, and precision medicine

D Yan, JE Gudjonsson, S Le, E Maverakis… - Journal of Investigative …, 2021 - Elsevier
Psoriasis is a chronic inflammatory condition characterized by systemic immune
dysregulation. Over the past several years, advances in genetics, microbiology …

[HTML][HTML] Luteolin attenuates imiquimod–induced psoriasis-like skin lesions in BALB/c mice via suppression of inflammation response

W Zhou, M Hu, X Zang, Q Liu, J Du, J Hu… - Biomedicine & …, 2020 - Elsevier
Psoriasis is considered as a common chronic immune-mediated skin disorder characterized
by abnormal keratinocyte proliferation. Luteolin, an anti-inflammatory natural flavonoid with …

Targeted ultrasound‐assisted cancer‐selective chemical labeling and subsequent cancer imaging using click chemistry

H Wang, M Gauthier, JR Kelly, RJ Miller… - Angewandte Chemie …, 2016 - Wiley Online Library
Metabolic sugar labeling followed by the use of reagent‐free click chemistry is an
established technique for in vitro cell targeting. However, selective metabolic labeling of the …