Carbon monoxide (CO) is attracting increasing attention because of its role as a
gasotransmitter with cytoprotective and homeostatic properties. Carbon monoxide releasing …

Carbon monoxide (CO) is increasingly being accepted as a cytoprotective and homeostatic
molecule with important signalling capabilities in physiological and pathophysiological …

The heme oxygenase-1 (HO-1) enzyme system remains an attractive therapeutic target for
the treatment of inflammatory conditions. HO-1, a cellular stress protein, serves a vital …

Nitric oxide (NO), carbon monoxide (CO) and hydrogen sulphide (H2S) together make up a
family of biologically active gases (the so-called 'gaseous triumvirate') with an increasingly …

Ischemia-reperfusion injury (IRI), which describes the cell damage and death that occurs
after blood and oxygen are restored to ischemic or hypoxic tissue, is a significant factor …

Heme oxygenase-1 (HO-1), a ubiquitous inducible stress-response protein, serves a major
metabolic function in heme turnover. HO activity cleaves heme to form biliverdin-IXα, carbon …

Carbon monoxide (CO) therapy has emerged as a hot topic under exploration in the field of
gas therapy as it shows the promise of treating various diseases. Due to the gaseous …

Heme oxygenases (HOs) are the rate-limiting enzymes in the catabolism of heme into
biliverdin, free iron, and carbon monoxide. Two genetically distinct isoforms of HO have …

The potential therapeutic effects of carbon monoxide in several disease states, and new
methodologies for CO delivery to specific targets is a topic of growing interest in mammalian …

Carbon monoxide (CO) is an endogenously produced gas that has gained recognition as a
biological signal transduction effector with properties similar, but not identical, to that of nitric …