The activation of the zygotic genome constitutes an essential process during early
embryogenesis that determines the overall progression of embryonic development. Zygotic …

Cellular stress plays a pivotal role in the onset of numerous human diseases. Consequently,
the removal of dysfunctional cells, which undergo excessive stress-induced damage via …

The conserved p38 MAPK family is activated by phosphorylation during stress responses
and inactivated by phosphatases. C. elegans PMK-1 p38 MAPK initiates innate immune …

Myofibre necrosis is a central pathogenic process in muscular dystrophies (MD). As post-
lesional regeneration cannot fully compensate for chronic myofibre loss, interstitial tissue …

Self-inflicted DNA strand breaks are canonically linked with cell death pathways and the
establishment of genetic diversity in immune and germline cells. Moreover, this form of DNA …

Mammalian dentition exhibits distinct heterodonty, with more simple teeth located in the
anterior area of the jaw and more complex teeth situated posteriorly. While some region …

The DNA-binding protein SATB2 is genetically linked to human intelligence. We studied its
influence on the three-dimensional (3D) epigenome by mapping chromatin interactions and …

Executioner caspases, such as caspase‐3, are known to induce apoptosis, but in other
contexts, they can control very different fates, including cell differentiation and neuronal …

Skeletal muscle development remarkably affects meat production and growth rate, regulated
by complex regulatory mechanisms in pigs. Specific AT sequence-binding protein 2 (SATB2) …

Skeletal muscle atrophy is an inevitable sequel of various factors such as cachexia, aging,
fasting, denervation, and microgravity. It is characterized by reduced muscle protein through …