RNA helicases comprise the largest family of enzymes involved in the metabolism of
mRNAs, the processing and fate of which rely on their packaging into messenger …

RNA-binding proteins (RBPs) are effectors and regulators of posttranscriptional gene
regulation (PTGR). RBPs regulate stability, maturation, and turnover of all RNAs, often …

The differentiation of primordial germ cells (PGCs) occurs during early embryonic
development and is critical for the survival and fitness of sexually reproducing species. Here …

Recent progress in high throughput sequencing and bioinformatic analysis and other
biochemical methods have fuelled our appreciation for the important role of microRNAs …

RNA helicases unwind their RNA substrates in an ATP-dependent reaction, and are central
to all cellular processes involving RNA. They have important roles in viral life cycles, where …

Cattleyak exhibit equivalent adaptability to harsh environment as yak and much higher
performances than yak. However, male infertility of cattleyak due to spermatogenic arrest …

Gonadotropin-regulated testicular RNA helicase (GRTH/DDX25), a testis-specific member of
the DEAD-box family, is an essential post-transcriptional regulator of spermatogenesis …

Mammalian spermatogenesis is a tightly coordinated process that gives rise to mature
spermatozoa capable of fertilising an ovum during sexual reproduction. A population of stem …

Non-obstructive azoospermia (NOA) is a severe form of male infertility, but its pathological
mechanisms and diagnostic biomarkers remain obscure. Since the dysregulation of RNA …

Post-transcriptional and translational control of specialized genes play a critical role in the
progression of spermatogenesis. During the early stages, mRNAs are actively transcribed …