Metal–Organic‐Framework‐Based Hydrogen‐Release Platform for Multieffective Helicobacter Pylori Targeting Therapy and Intestinal Flora Protective Capabilities

W Zhang, Y Zhou, Y Fan, R Cao, Y Xu… - Advanced …, 2022 - Wiley Online Library
Helicobacter pylori (H. pylori) infection is the leading cause of chronic gastritis, peptic ulcer,
and gastric cancer. Antibiotics, as traditional method for eliminating H. pylori, have no …

[HTML][HTML] Mathematical modeling of regulatory networks of intracellular processes–Aims and selected methods

M Kardynska, D Kogut, M Pacholczyk… - Computational and …, 2023 - Elsevier
Regulatory networks structure and signaling pathways dynamics are uncovered in time-and
resource consuming experimental work. However, it is increasingly supported by modeling …

[HTML][HTML] Photothermal switch by gallic acid-calcium grafts synthesized by coordination chemistry for sequential treatment of bone tumor and regeneration

X Hou, L Zhang, Y Chen, Z Liu, X Zhao, B Lu, Y Luo… - Biomaterials, 2025 - Elsevier
The residual bone tumor and defects which is caused by surgical therapy of bone tumor is a
major and important problem in clinicals. And the sequential treatment for irradiating …

Mathematical Modeling Support for Lung Cancer Therapy—A Short Review

J Smieja - International Journal of Molecular Sciences, 2023 - mdpi.com
The paper presents a review of models that can be used to describe dynamics of lung
cancer growth and its response to treatment at both cell population and intracellular …

HSF1 Can Prevent Inflammation following Heat Shock by Inhibiting the Excessive Activation of the ATF3 and JUN&FOS Genes

P Janus, P Kuś, N Vydra, A Toma-Jonik, T Stokowy… - Cells, 2022 - mdpi.com
Heat Shock Factor 1 (HSF1), a transcription factor frequently overexpressed in cancer, is
activated by proteotoxic agents and participates in the regulation of cellular stress response …

Genome-wide detection of copy number variants in chinese indigenous horse breeds and verification of cnv-overlapped genes related to heat adaptation of the …

M Wang, Y Liu, X Bi, H Ma, G Zeng, J Guo, M Guo… - Genes, 2022 - mdpi.com
In the present study, genome-wide CNVs were detected in a total of 301 samples from 10
Chinese indigenous horse breeds using the Illumina Equine SNP70 Bead Array, and the …

Expression of Truncated Products at the 5′-Terminal Region of RIPK2 and Evolutive Aspects that Support Their Biological Importance

UMM Villagra, BR da Cunha… - Genome Biology and …, 2024 - academic.oup.com
Alternative splicing is the process of generating different mRNAs from the same primary
transcript, which contributes to increase the transcriptome and proteome diversity. Abnormal …

Increased HSF1 promotes infiltration and metastasis in cervical cancer via enhancing MTDH-VEGF-C expression

X Shi, Z Deng, S Wang, S Zhao, L Xiao… - OncoTargets and …, 2021 - Taylor & Francis
Purpose To explore the molecular mechanism of promoting cervical cancer by HSF1 in vivo
and in vitro. Methods The expression of HSF1 in 110 paraffin-embedded cervical cancer …

Novel Ser74 of NF-κB/IκBα phosphorylated by MAPK/ERK regulates temperature adaptation in oysters

C Wang, Z Jiang, M Du, R Cong, W Wang… - Cell Communication and …, 2024 - Springer
Abstract Phosphorylation of Ser32 and Ser36 controls the degradation of IκBα is the
conserved cascade mechanisms of immune core signaling pathway, NF-κB pathway in …

The significant mechanism and treatments of cell death in heatstroke

Z Wang, J Zhu, D Zhang, J Lv, L Wu, Z Liu - Apoptosis, 2024 - Springer
With global warming, extreme environmental heat is becoming a social issue of concern,
which can cause adverse health results including heatstroke (HS). Severe heat stress is …