Polyunsaturated fatty acids and fatty acid-derived lipid mediators: Recent advances in the understanding of their biosynthesis, structures, and functions
Polyunsaturated fatty acids (PUFAs) are structural components of membrane phospholipids,
and influence cellular function via effects on membrane properties, and also by acting as a …
and influence cellular function via effects on membrane properties, and also by acting as a …
Oxidative stress and cancer
JE Klaunig - Current pharmaceutical design, 2018 - ingentaconnect.com
Background: Cancer is considered a major cause of death worldwide. The etiology of cancer
is linked to environmental and genetic inheritance causes. Approximately 90 percent of all …
is linked to environmental and genetic inheritance causes. Approximately 90 percent of all …
Assessment of lipid peroxidation by measuring malondialdehyde (MDA) and relatives in biological samples: Analytical and biological challenges
D Tsikas - Analytical biochemistry, 2017 - Elsevier
Abstract Malondialdehyde (MDA), 4-hydroxy-nonenal (HNE) and the F 2-isoprostane 15 (S)-
8-iso-prostaglandin F 2α (15 (S)-8-iso-PGF 2α) are the best investigated products of lipid …
8-iso-prostaglandin F 2α (15 (S)-8-iso-PGF 2α) are the best investigated products of lipid …
Peripheral markers of depression
A Nobis, D Zalewski, N Waszkiewicz - Journal of clinical medicine, 2020 - mdpi.com
Major Depressive Disorder (MDD) is a leading cause of disability worldwide, creating a high
medical and socioeconomic burden. There is a growing interest in the biological …
medical and socioeconomic burden. There is a growing interest in the biological …
[HTML][HTML] Metabolic slowing and reduced oxidative damage with sustained caloric restriction support the rate of living and oxidative damage theories of aging
Calorie restriction (CR) is a dietary intervention with potential benefits for healthspan
improvement and lifespan extension. In 53 (34 CR and 19 control) non-obese adults, we …
improvement and lifespan extension. In 53 (34 CR and 19 control) non-obese adults, we …
Clinical relevance of biomarkers of oxidative stress
J Frijhoff, PG Winyard, N Zarkovic… - Antioxidants & redox …, 2015 - liebertpub.com
Significance: Oxidative stress is considered to be an important component of various
diseases. A vast number of methods have been developed and used in virtually all diseases …
diseases. A vast number of methods have been developed and used in virtually all diseases …
Lipid peroxidation: production, metabolism, and signaling mechanisms of malondialdehyde and 4‐hydroxy‐2‐nonenal
Lipid peroxidation can be described generally as a process under which oxidants such as
free radicals attack lipids containing carbon‐carbon double bond (s), especially …
free radicals attack lipids containing carbon‐carbon double bond (s), especially …
Oxidative stress, inflammation and treatment response in major depression
Objective Increased inflammation and oxidative stress have been shown in Major
Depressive Disorder (MDD), although there is significant heterogeneity across studies …
Depressive Disorder (MDD), although there is significant heterogeneity across studies …
Measurement of reactive oxygen species, reactive nitrogen species, and redox-dependent signaling in the cardiovascular system: a scientific statement from the …
Reactive oxygen species and reactive nitrogen species are biological molecules that play
important roles in cardiovascular physiology and contribute to disease initiation …
important roles in cardiovascular physiology and contribute to disease initiation …
Vitamin A and vitamin E: will the real antioxidant please stand up?
WS Blaner, IO Shmarakov… - Annual review of nutrition, 2021 - annualreviews.org
Vitamin A, acting through its metabolite, all-trans-retinoic acid, is a potent transcriptional
regulator affecting expression levels of hundreds of genes through retinoic acid response …
regulator affecting expression levels of hundreds of genes through retinoic acid response …