Airflow and particle transport in the human respiratory system

C Kleinstreuer, Z Zhang - Annual review of fluid mechanics, 2010 - annualreviews.org
Airflows in the nasal cavities and oral airways are rather complex, possibly featuring a
transition to turbulent jet-like flow, recirculating flow, Dean's flow, vortical flows, large …

A review of respiratory anatomical development, air flow characterization and particle deposition

MS Islam, G Paul, HX Ong, PM Young, YT Gu… - International journal of …, 2020 - mdpi.com
The understanding of complex inhalation and transport processes of pollutant particles
through the human respiratory system is important for investigations into dosimetry and …

Characteristics of the turbulent laryngeal jet and its effect on airflow in the human intra-thoracic airways

CL Lin, MH Tawhai, G McLennan… - Respiratory physiology & …, 2007 - Elsevier
A computational fluid dynamics technique is applied to understand the relative importance of
the upper and intra-thoracic airways and their role in determining central airflow patterns …

[图书][B] Aerosols handbook: measurement, dosimetry, and health effects

LS Ruzer, NH Harley - 2012 - books.google.com
With the rapid growth of the nanotechnology industry, the need to understand the biological
effects of aerosol exposure has become increasingly important. Featuring contributions by …

Role of CFD based in silico modelling in establishing an in vitro-in vivo correlation of aerosol deposition in the respiratory tract

F Huang, Q Zhu, X Zhou, D Gou, J Yu, R Li… - Advanced drug delivery …, 2021 - Elsevier
Effective evaluation and prediction of aerosol transport deposition in the human respiratory
tracts are critical to aerosol drug delivery and evaluation of inhalation products …

Regional aerosol deposition in the human airways: The SimInhale benchmark case and a critical assessment of in silico methods

P Koullapis, SC Kassinos, J Muela… - European Journal of …, 2018 - Elsevier
Regional deposition effects are important in the pulmonary delivery of drugs intended for the
topical treatment of respiratory ailments. They also play a critical role in the systemic delivery …

In vitro intersubject and intrasubject deposition measurements in realistic mouth–throat geometries

B Grgic, WH Finlay, PKP Burnell, AF Heenan - Journal of Aerosol Science, 2004 - Elsevier
This paper presents regional and total deposition measurements in several realistic mouth
and throat geometries and demonstrates the effects of intrasubject and intersubject …

Tracheal stenosis: a flow dynamics study

M Brouns, ST Jayaraju, C Lacor… - Journal of Applied …, 2007 - journals.physiology.org
Patients referred for treatment of tracheal stenosis typically are asymptomatic until critical
narrowing of the airway occurs, which then requires immediate intervention. To understand …

Effects of the laryngeal jet on nano-and microparticle transport and deposition in an approximate model of the upper tracheobronchial airways

J Xi, PW Longest, TB Martonen - Journal of Applied …, 2008 - journals.physiology.org
The extent to which laryngeal-induced flow features penetrate into the upper
tracheobronchial (TB) airways and their related impact on particle transport and deposition …

Regional aerosol deposition and flow measurements in an idealized mouth and throat

B Grgic, WH Finlay, AF Heenan - Journal of Aerosol Science, 2004 - Elsevier
Extrathoracic deposition was studied using an idealized average human mouth and throat
replica. Effects of particle size, flow rate and flow Reynolds number were examined using …