Antioxidant mechanisms in nonalcoholic fatty liver disease

W Liu, SS Baker, RD Baker, L Zhu - Current drug targets, 2015 - ingentaconnect.com
Nonalcoholic fatty liver disease (NAFLD) represents a broad spectrum of histological
abnormalities with clinical presentations ranging from hepatic steatosis to nonalcoholic …

Metabolic dysfunction-associated steatotic liver disease-induced changes in the antioxidant system: a review

G Svobodová, M Horní, E Velecká, I Boušová - Archives of Toxicology, 2024 - Springer
Metabolic dysfunction-associated steatotic liver disease (MASLD) is a heterogeneous
condition characterized by liver steatosis, inflammation, consequent fibrosis, and cirrhosis …

Betaine modulates oxidative stress, inflammation, apoptosis, autophagy, and Akt/mTOR signaling in methionine-choline deficiency-induced fatty liver disease

M Veskovic, D Mladenovic, M Milenkovic, J Tosic… - European journal of …, 2019 - Elsevier
We examined the effects of betaine, an endogenous and dietary methyl donor essential for
the methionine-homocysteine cycle, on oxidative stress, inflammation, apoptosis, and …

Hepatic metabolomics reveals that liver injury increases PCB 126-induced oxidative stress and metabolic dysfunction

P Deng, J Barney, MC Petriello, AJ Morris, B Wahlang… - Chemosphere, 2019 - Elsevier
The deleterious effects of PCB 126 are complex, and the role of the liver in modifying toxic
insult is not well understood. We utilized metabolomics approaches to compare liver …

Statins increase mitochondrial and peroxisomal fatty acid oxidation in the liver and prevent non-alcoholic steatohepatitis in mice

HS Park, JE Jang, MS Ko, SH Woo… - Diabetes & …, 2016 - synapse.koreamed.org
Background Non-alcoholic fatty liver disease is the most common form of chronic liver
disease in industrialized countries. Recent studies have highlighted the association …

Beneficial effects of curcumin nano-emulsion on spermatogenesis and reproductive performance in male rats under protein deficient diet model: Enhancement of …

OAH Ahmed-Farid, M Nasr, RF Ahmed… - Journal of Biomedical …, 2017 - Springer
Background Malnutrition resulting from protein and calorie deficiency continues to be a
major concern worldwide especially in developing countries. Specific deficiencies in the …

Protective capabilities of silymarin and inulin nanoparticles against hepatic oxidative stress, genotoxicity and cytotoxicity of Deoxynivalenol in rats

MA Abdel-Wahhab, AA El-Nekeety, AS Salman… - Toxicon, 2018 - Elsevier
Deoxynivalenol (DON) is a Fusarium mycotoxin that frequently contaminates cereal and
cereal-based food and induces liver injury. This study evaluated the protective role of …

Is nonalcoholic fatty liver disease an endogenous alcoholic fatty liver disease?–A mechanistic hypothesis

IC de Medeiros, JG de Lima - Medical Hypotheses, 2015 - Elsevier
Nonalcoholic fatty liver disease (NAFLD) and alcoholic fatty liver disease (AFLD) are so
similar that only a detailed history of alcohol intake can distinguish one from the other …

Gd-EOB-DTPA-enhanced-MR imaging in the inflammation stage of nonalcoholic steatohepatitis (NASH) in mice

T Yamada, A Obata, Y Kashiwagi, T Rokugawa… - Magnetic resonance …, 2016 - Elsevier
Objective The purpose of this study is to investigate the correlation between the liver kinetics
of gadolinium-ethoxybenzyl-diethylenetriamine pentaacetic acid (Gd-EOB-DTPA) and liver …

The effects of dietary methionine restriction on the function and metabolic reprogramming in the liver and brain–implications for longevity

D Mladenović, T Radosavljević, D Hrnčić… - Reviews in the …, 2019 - degruyter.com
Methionine is an essential sulphur-containing amino acid involved in protein synthesis,
regulation of protein function and methylation reactions. Dietary methionine restriction (0.12 …