[HTML][HTML] Dysregulation of epigenetic mechanisms of gene expression in the pathologies of hyperhomocysteinemia

J Perła-Kaján, H Jakubowski - International journal of molecular sciences, 2019 - mdpi.com
Hyperhomocysteinemia (HHcy) exerts a wide range of biological effects and is associated
with a number of diseases, including cardiovascular disease, dementia, neural tube defects …

A meta-analysis of epigenome-wide association studies on pregnancy vitamin B12 concentrations and offspring DNA methylation

GS Monasso, TT Hoang, G Mancano… - Epigenetics, 2023 - Taylor & Francis
Circulating vitamin B12 concentrations during pregnancy are associated with offspring
health. Foetal DNA methylation changes could underlie these associations. Within the …

[HTML][HTML] Effect of ABCA1 promoter methylation on premature coronary artery disease and its relationship with inflammation

F An, C Liu, X Wang, T Li, H Fu, B Bao, H Cong… - BMC Cardiovascular …, 2021 - Springer
Background ATP-binding cassette transporter A1 (ABCA1) plays a major role in high-density
lipoprotein (HDL) metabolism and reverse cholesterol transport (RCT) and exerts anti …

Interaction between plasma homocysteine and the MTHFR C.677C > T polymorphism is associated with site‐specific changes in DNA methylation in humans

AJ Nash, PR Mandaviya, MJ Dib… - The FASEB …, 2019 - Wiley Online Library
One‐carbon metabolism provides a direct link among dietary folate/vitamin B12 exposure,
the activity of the enzyme methylenetetrahydrofolate reductase (MTHFR), and epigenetic …

Hypermethylation of ERа-A gene and high serum homocysteine level are correlated with cognitive impairment in white matter hyperintensity patients

HY Sun, QM Qu - QJM: An International Journal of Medicine, 2019 - academic.oup.com
Objective To investigate the methylation status in promoter region of estrogen receptor alpha
(ERа)-A gene and its relation with plasma homocysteine (Hcy) level and cognitive …

Genome-wide analysis of DNA methylation and its relationship with serum homocysteine levels in patients with hypertension

M Zhu, D An, J Zhang, X Tang, Y Wang… - Journal of …, 2023 - journals.lww.com
Background: Homocysteine (Hcy) is an independent risk factor for cardiovascular diseases,
and elevated plasma Hcy levels could aggravate vascular injury in hypertension …