Recent advances in high-throughput technologies have enabled the profiling of multiple
layers of a biological system, including DNA sequence data (genomics), RNA expression …

Encouraging advances are being made in cancer immunotherapy modeling, especially in
the key areas of developing personalized treatment strategies based on individual patient …

The biopharmaceutical industry continuously seeks to optimize the critical quality attributes
to maintain the reliability and cost‐effectiveness of its products. Such optimization demands …

Metformin is the primary drug for type 2 diabetes treatment and a promising candidate for
other disease treatment. It has significant deviations between individuals in therapy …

Highlights•Personalized medicine is hindered by poor translatability from preclinical
research.•Artificial intelligence (AI) may improve personalized drug development.• …

The clinical management of malignant tumours is challenging, often leading to severe
adverse effects and death. Drug resistance (DR) antagonises the effectiveness of …

Advances in (bio) medicine and technological innovations make it possible to combine high-
dimensional, heterogeneous health data to better understand causes of diseases and make …

In many scientific and technological contexts, we have only a poor understanding of the
structure and details of appropriate mathematical models. We often, therefore, need to …

Diabetes mellitus, stemming from either insulin resistance or inadequate insulin secretion,
represents a complex ailment that results in prolonged hyperglycemia and severe …

Increasing genome-wide data in biological sciences and medicine has contributed to the
development of a variety of visualization tools. Several automatic, semiautomatic, and …