Engineering spatiotemporal control in vascularized tissues

A Khanna, BP Oropeza, NF Huang - Bioengineering, 2022 - mdpi.com
A major challenge in engineering scalable three-dimensional tissues is the generation of a
functional and developed microvascular network for adequate perfusion of oxygen and …

Improving vascular regeneration performance of electrospun poly (ε-caprolactone) vascular grafts via synergistic functionalization with VE-cadherin/VEGF

Y Zhang, K Xu, D Zhi, M Qian, K Liu, Q Shuai… - Advanced Fiber …, 2022 - Springer
In vivo, vascular endothelial growth factor (VEGF) and vascular endothelial cadherin (VE-
cadherin) co-regulate the dynamic organization of endothelial cells during vascular …

Prevascularization techniques for dental pulp regeneration: potential cell sources, intercellular communication and construction strategies

Q Ruan, S Tan, L Guo, D Ma, J Wen - Frontiers in Bioengineering and …, 2023 - frontiersin.org
One of the difficulties of pulp regeneration is the rapid vascularization of transplanted
engineered tissue, which is crucial for the initial survival of the graft and subsequent pulp …

Perivascular and endomysial macrophages expressing VEGF and CXCL12 promote angiogenesis in anti-HMGCR immune-mediated necrotizing myopathy

A Lia, T Annese, M Fornaro, M Giannini… - …, 2022 - academic.oup.com
Objectives To study the phenotype of macrophage infiltrates and their role in angiogenesis
in different idiopathic inflammatory myopathies (IIMs). Methods The density and distribution …

[HTML][HTML] FOXO1-mTOR pathway in vascular pericyte regulates the formation of type H vessels to control bone metabolism

C Cheng, M Deng, C Cheng, H Wu, Y Wang… - Journal of Orthopaedic …, 2024 - Elsevier
Background As the population aging progresses, age-related osteoporosis has become one
of the most common and severe chronic degenerative diseases. Due to insufficient …

Notoginsenoside R1 decreases intraplaque neovascularization by governing pericyte‐endothelial cell communication via Ang1/Tie2 axis in atherosclerosis

Y Li, L Zhang, W Yang, L Lin, J Pan, M Lu… - Phytotherapy …, 2024 - Wiley Online Library
Atherosclerosis represents the major cause of mortality worldwide and triggers higher risk of
acute cardiovascular events. Pericytes‐endothelial cells (ECs) communication is …

Proanthocyanidin surface preconditioning of dental pulp stem cell spheroids enhances dimensional stability and biomineralization in vitro

S Yang, AYP Leung, Z Wang, CKY Yiu… - International …, 2024 - Wiley Online Library
Aim Lack of adequate mechanical strength and progressive shrinkage over time remain
challenges in scaffold‐free microtissue‐based dental pulp regeneration. Surface collagen …

Intrathecal Fumagillin Alleviates Chronic Neuropathy-Induced Nociceptive Sensitization and Modulates Spinal Astrocyte-Neuronal Glycolytic and Angiogenic Proteins

ZH Wen, ZS Wu, HJ Cheng, SY Huang, SH Tang… - Molecular …, 2025 - Springer
Nociceptive sensitization is accompanied by the upregulation of glycolysis in the central
nervous system in neuropathic pain. Growing evidence has demonstrated glycolysis and …

Dental pulp stem cells‐based therapy for the oviduct injury via immunomodulation and angiogenesis in vivo

L Luo, Z Xing, X Liao, Y Li, Y Luo, Y Ai, Y He… - Cell …, 2022 - Wiley Online Library
Objectives As a result of the current limitation of therapeutic strategies, the repair and
regeneration of oviduct injuries required an alternative treatment. We present a novel …

Ang1/Tie2/VE-Cadherin signaling regulates DPSCs in vascular maturation

Y Zhang, S Lin, J Liu, Q Chen, J Kang… - Journal of Dental …, 2024 - journals.sagepub.com
Adding dental pulp stem cells (DPSCs) to vascular endothelial cell–formed vessel-like
structures can increase the longevity of these vessel networks. DPSCs display pericyte-like …