During early mammalian embryonic development, trophoblast cells play an essential role in
establishing cell–cell interactions at the maternal–fetal interface to ensure a successful …

Human pluripotent and trophoblast stem cells have been essential alternatives to
blastocysts for understanding early human development 1, 2, 3, 4. However, these simple …

We aimed to investigate whether molecular clues from the extracellular matrix (ECM) can
induce oral epithelial differentiation of pluripotent stem cells. Mouse embryonic stem cells …

诱导性多能干细胞(induced pluripotent stem cells, iPSCs) 是指通过导入特定的转录因子将终
末分化的体细胞重编程为可以无限增殖更新并具有分化为三胚层多种细胞类型的一类干细胞系 …

Generating patient-specific stem cells representing the onset of development has become
possible since the discovery of somatic cell reprogramming into induced pluripotent stem …

The subcutaneous tissue of animals contains different cell types, and different cells have
different requirements for cryopreservation. This establishes obstacles that need to be …

Induce pluripotent stem cells (iPSCs) refer to a class of stem cell lines that reprogram
terminally differentiated somatic cells into infinite proliferation and regeneration and have …

Terminally differentiated somatic cells can be reprogrammed into an embryonic stem cell-
like state by the forced expression of four transcription factors: Oct4, Klf4, Sox2, and c-Myc …