Cytokine members of the IL‐12 family have attracted enormous attention in the last few
years, with IL‐35 being the one of the most attractive‐suppressive cytokine. IL‐35 is an …

IL-35 is a new anti-inflammatory cytokine identified in 2007, which inhibits inflammation and
immune responses by inducing regulatory T cells and regulatory B cells and suppressing …

Dendritic cells (DCs) play a central role in shaping immunogenic as well as tolerogenic
adaptive immune responses and thereby dictate the outcome of adaptive immunity. Here …

The aim of this study was to analyze the relationship between immunological markers and
the dysfunction of cutaneous microcirculation in young patients with type 1 diabetes. The …

Abstract Interleukin 35 (IL-35), a cytokine secreted by regulatory T (Treg) cells from the
differentiation of conventional CD4+ T cells, is a member of the IL-12 family. The IL-12 family …

One vision-threatening side effect of systematic diabetes mellitus is diabetic retinopathy
(DR). Recent studies have revealed that the development and progression of DR depend …

Small synthetic oligodeoxynucleotides (ODNs) can mimic microbial nucleic acids by
interacting with receptor systems and promoting immunostimulatory activities. Nevertheless …

Diabetes is a common metabolic disease characterized by an imbalance in blood glucose
levels. The pathogenesis of diabetes involves the essential role of cytokines, particularly the …

Autoimmune thyroid disease (AIT) is the most frequently linked autoimmune condition to
type 1 diabetes (T1D). The analysis of immune profiles could provide valuable insights into …

A chronic autoimmune condition known as type 1 diabetes mellitus (T1DM) has
characteristics marked by a gradual immune-mediated deterioration of the β-cells that …