[HTML][HTML] A comprehensive and biophysically detailed computational model of the whole human heart electromechanics

M Fedele, R Piersanti, F Regazzoni, M Salvador… - Computer Methods in …, 2023 - Elsevier
While ventricular electromechanics is extensively studied in both physiological and
pathological conditions, four-chamber heart models have only been addressed recently; …

lifex-cfd: An open-source computational fluid dynamics solver for cardiovascular applications

PC Africa, I Fumagalli, M Bucelli, A Zingaro… - Computer Physics …, 2024 - Elsevier
Computational fluid dynamics (CFD) is an important tool for the simulation of the
cardiovascular function and dysfunction. Due to the complexity of the anatomy, the …

lifex-ep: a robust and efficient software for cardiac electrophysiology simulations

PC Africa, R Piersanti, F Regazzoni, M Bucelli… - BMC …, 2023 - Springer
Background Simulating the cardiac function requires the numerical solution of multi-physics
and multi-scale mathematical models. This underscores the need for streamlined, accurate …

A comprehensive mathematical model for cardiac perfusion

A Zingaro, C Vergara, L Dede', F Regazzoni… - Scientific Reports, 2023 - nature.com
The aim of this paper is to introduce a new mathematical model that simulates myocardial
blood perfusion that accounts for multiscale and multiphysics features. Our model …

[HTML][HTML] Whole-heart modelling with valves in a fluid–structure interaction framework

L Feng, H Gao, X Luo - Computer Methods in Applied Mechanics and …, 2024 - Elsevier
Computational modelling of whole-heart function is a useful tool to study heart mechanics
and haemodynamics. Many existing heart models focus on electromechanical aspect …

A comprehensive stroke risk assessment by combining atrial computational fluid dynamics simulations and functional patient data

A Zingaro, Z Ahmad, E Kholmovski, K Sakata… - Scientific reports, 2024 - nature.com
Stroke, a major global health concern often rooted in cardiac dynamics, demands precise
risk evaluation for targeted intervention. Current risk models, like the CHA 2 DS 2-VASc …

[HTML][HTML] A stable loosely-coupled scheme for cardiac electro-fluid-structure interaction

M Bucelli, MG Gabriel, A Quarteroni, G Gigante… - Journal of …, 2023 - Elsevier
We present a loosely coupled scheme for the numerical simulation of the cardiac electro-
fluid-structure interaction problem, whose solution is typically computationally intensive due …

Modeling isovolumetric phases in cardiac flows by an augmented resistive immersed implicit surface method

A Zingaro, M Bucelli, I Fumagalli… - International Journal …, 2023 - Wiley Online Library
A major challenge in the computational fluid dynamics modeling of the heart function is the
simulation of isovolumetric phases when the hemodynamics problem is driven by a …

[HTML][HTML] Echocardiogram-based ventricular isogeometric cardiac analysis using multi-patch fitted NURBS

R Willems, L Verberne, O van der Sluis… - Computer Methods in …, 2024 - Elsevier
Monitoring the cardiac function often relies on non-invasive vital measurements,
electrocardiograms, and low-resolution echocardiograms. The monitoring data can be …

Quantification of total uncertainty in the physics-informed reconstruction of CVSim-6 physiology

M De Florio, Z Zou, DE Schiavazzi… - arXiv preprint arXiv …, 2024 - arxiv.org
When predicting physical phenomena through simulation, quantification of the total
uncertainty due to multiple sources is as crucial as making sure the underlying numerical …