BackgroundPeripheral low-grade inflammation in depression is increasingly seen as a
therapeutic target. We aimed to establish the prevalence of low-grade inflammation in …

Low-grade inflammation plays a role not only in the pathogenesis of major depressive
disorder (MDD) but probably also in the poor responsiveness to regular antidepressants …

Abstract Glucose 6-phosphate dehydrogenase (G6PD) deficiency facilitates human
coronavirus infection due to glutathione depletion. G6PD deficiency may especially …

Abstract N-acetyl-L-cysteine (NAC) is a compound of increasing interest in the treatment of
psychiatric disorders. Primarily through its antioxidant, anti-inflammatory, and glutamate …

Accumulating data highlight the contribution of brain mitochondria and bioenergetics to
psychiatric disorders and stress-related pathologies. Although anxiety has not received …

Bipolar disorder's core feature is the pathological disturbances in mood, often accompanied
by disrupted thinking and behavior. Its complex and heterogeneous etiology implies that a …

BackgroundMood disorders, ie major depressive disorder (MDD) and bipolar disorders, are
leading sources of disability worldwide. Currently available treatments do not yield …

Introduction: Individuals with bipolar disorder (BD) have higher rates of unhealthy lifestyles
and risk for medical comorbidities Research currently suggests that dietary factors may play …

N‐acetylcysteine (NAC) is a well‐known and safe mucolytic agent, also used in patients with
paracetamol overdose. In addition to these effects, recent preclinical and clinical studies …

Depression is a common but serious mental illness; meanwhile, it is also an inflammatory
disorder. Toll-like receptor 4 (TLR4), as the pattern recognition receptor, has been shown to …