[HTML][HTML] Homocysteine metabolism as the target for predictive medical approach, disease prevention, prognosis, and treatments tailored to the person

L Koklesova, A Mazurakova, M Samec, K Biringer… - EPMA Journal, 2021 - Springer
Homocysteine (Hcy) metabolism is crucial for regulating methionine availability, protein
homeostasis, and DNA-methylation presenting, therefore, key pathways in post-genomic …

[HTML][HTML] Pathophysiologic relationship between Alzheimer's disease, cerebrovascular disease, and cardiovascular risk: a review and synthesis

CY Santos, PJ Snyder, WC Wu, M Zhang… - Alzheimer's & Dementia …, 2017 - Elsevier
As the population ages due to demographic trends and gains in life expectancy, the
incidence and prevalence of dementia increases, and the need to understand the etiology …

[HTML][HTML] The controversial role of homocysteine in neurology: from labs to clinical practice

R Moretti, P Caruso - International journal of molecular sciences, 2019 - mdpi.com
Homocysteine (Hcy) is a sulfur-containing amino acid that is generated during methionine
metabolism. Physiologic Hcy levels are determined primarily by dietary intake and vitamin …

Antioxidants for male subfertility

W de Ligny, RM Smits… - Cochrane Database …, 2022 - cochranelibrary.com
Background The inability to have children affects 10% to 15% of couples worldwide. A male
factor is estimated to account for up to half of the infertility cases with between 25% to 87% of …

Homocysteine and hyperhomocysteinaemia

BL Zaric, M Obradovic, V Bajic… - Current medicinal …, 2019 - ingentaconnect.com
Homocysteine (Hcy) is a thiol group containing the amino acid, which naturally occurs in all
humans. Hcy is degraded in the body through two metabolic pathways, while a minor part is …

[HTML][HTML] Role of homocysteine in the development of cardiovascular disease

P Ganguly, SF Alam - Nutrition journal, 2015 - Springer
It is well known that neuronal damage following a stroke has been attributed to the over
stimulation of excitatory amino acids such as glutamate and aspartate through activation of …

Herbal medicine: biomolecular and clinical aspects

IFF Benzie, S Wachtel-Galor - 2011 - books.google.com
The global popularity of herbal supplements and the promise they hold in treating various
disease states has caused an unprecedented interest in understanding the molecular basis …

Decreased endogenous production of hydrogen sulfide accelerates atherosclerosis

S Mani, H Li, A Untereiner, L Wu, G Yang, RC Austin… - Circulation, 2013 - Am Heart Assoc
Background—Cystathionine γ-lyase (CSE) produces hydrogen sulfide (H2S) in the
cardiovascular system. The deficiency of CSE in mice leads to a decreased endogenous …

Deep vein thrombosis

PA Kyrle, S Eichinger - The Lancet, 2005 - thelancet.com
Deep vein thrombosis and its sequelae pulmonary embolism and post-thrombotic syndrome
are some of the most common disorders. A thrombus either arises spontaneously or is …

Current concepts in the etiology and treatment of Behçet disease

C Evereklioglu - Survey of ophthalmology, 2005 - Elsevier
Behçet disease is an idiopathic, multisystem, chronic, and recurrent disease characterized
by exacerbations alternating with phases of quiescence, episodic panuveitis, and …