Aciclovir: a reappraisal of its antiviral activity, pharmacokinetic properties and therapeutic efficacy

AJ Wagstaff, D Faulds, KL Goa - Drugs, 1994 - Springer
Aciclovir (acyclovir) is a nucleoside analogue with antiviral activity in vitro against the herpes
simplex viruses (HSV), varicella zoster virus (VZV), Epstein-Barr virus (EBV) …

Pregnancy in chronic renal insufficiency and end-stage renal disease

S Hou - American Journal of Kidney Diseases, 1999 - Elsevier
Childbearing is important to women with renal disease, but pregnancy has generally been
regarded as very high risk in these women. In this review, an attempt is made to clarify the …

ACG clinical guideline: liver disease and pregnancy

TT Tran, J Ahn, NS Reau - Official journal of the American College …, 2016 - journals.lww.com
Consultation for liver disease in pregnant women is a common and oftentimes vexing
clinical consultation for the gastroenterologist. The challenge lies in the need to consider the …

[图书][B] Chemically induced birth defects

J Schardein - 2000 - taylorfrancis.com
This thoroughly revised and updated reference addresses the drugs and chemicals causing
malformations and congenital anomalies in the human fetus-comprehensively reviewing …

Pregnancy outcomes following systemic prenatal acyclovir exposure: conclusions from the international acyclovir pregnancy registry, 1984–1999

KM Stone, R Reiff‐Eldridge, AD White… - … Research Part A …, 2004 - Wiley Online Library
BACKGROUND Oral acyclovir is commonly used for genital herpes and other herpesvirus
infections. Data on potential fetal risk are extremely limited. From 1984 to 1998, the Acyclovir …

The AED (antiepileptic drug) pregnancy registry: a 6-year experience

LB Holmes, DF Wyszynski, E Lieberman - Archives of neurology, 2004 - jamanetwork.com
Background Pregnancy registries are a new method for assessing the fetal risks from
exposures in pregnancy. We present the findings of the North American AED (antiepileptic …

The congenital varicella syndrome

A Sauerbrei, P Wutzler - Journal of Perinatology, 2000 - nature.com
Maternal varicella during the first two trimesters of pregnancy may cause the congenital
varicella syndrome (CVS). After infection in the first 20 weeks' gestation, the incidence is …

Herpes simplex virus and Epstein-Barr virus infections in pregnancy: consequences of neonatal or intrauterine infection

M Avgil, A Ornoy - Reproductive Toxicology, 2006 - Elsevier
Herpes simplex virus (HSV) type 1/2 and Epstein-Barr virus (EBV) belong to the human
herpes viruses and are among the most ubiquitous viruses in the adult population. In spite of …

Liver diseases during pregnancy

K Ma, D Berger, N Reau - Clinics in liver disease, 2019 - liver.theclinics.com
Liver diseases during pregnancy pose a unique clinical challenge as they can affect the
lives of both the mother and unborn child. Although severe liver disease is rare, pregnancy …

Neonatal herpes simplex virus infections

CM Rudnick, GS Hoekzema - American family physician, 2002 - aafp.org
Neonatal herpes simplex virus infections can result in serious morbidity and mortality. Many
of the infections result from asymptomatic cervical shedding of virus after a primary episode …