2023 GEIS Guidelines for gastrointestinal stromal tumors

C Serrano, J Martín-Broto… - Therapeutic …, 2023 - journals.sagepub.com
Gastrointestinal stromal tumor (GIST) is the most common malignant neoplasm of
mesenchymal origin. GIST spans a wide clinical spectrum that ranges from tumors with …

Current status of and future prospects for the treatment of unresectable or metastatic gastrointestinal stromal tumours

Y Naito, T Nishida, T Doi - Gastric Cancer, 2023 - Springer
Gastrointestinal stromal tumours (GISTs) are soft-tissue sarcomas of the gastrointestinal
tract. Surgery is the standard treatment for localised disease, but the risk of relapse and …

[HTML][HTML] A randomized study of 6 versus 3 years of adjuvant imatinib in patients with localized GIST at high risk of relapse

JY Blay, C Schiffler, O Bouché, M Brahmi, F Duffaud… - Annals of …, 2024 - Elsevier
Background The administration of adjuvant imatinib during 3 years is indicated after
resection of primary localized GIST at high risk of recurrence, but many patients relapse …

Evaluation of systemic treatment options for gastrointestinal stromal tumours

M Golčić, RL Jones, P Huang, A Napolitano - Cancers, 2023 - mdpi.com
Simple Summary This review summarises the systemic treatment options available for
patients with gastrointestinal stromal tumours (GIST). While surgical treatment is …

KIT and PDGFRA Variants and the Survival of Patients with Gastrointestinal Stromal Tumor Treated with Adjuvant Imatinib

H Joensuu - Cancers, 2023 - mdpi.com
Simple Summary Gastrointestinal stromal tumor (GIST) is the most common type of sarcoma
that arises from the gastrointestinal tract, most frequently from the stomach. The malignancy …

KIT and PDGFRA Mutations and Survival of Gastrointestinal Stromal Tumor Patients Treated with Adjuvant Imatinib in a Randomized Trial

H Joensuu, E Wardelmann, M Eriksson… - Clinical Cancer …, 2023 - AACR
Purpose: Limited data are available about the influence of KIT and PDGFRA mutations on
overall survival (OS) of patients with gastrointestinal stromal tumor (GIST) treated with …

Vitamin D supplementation during intensive care unit stay is associated with improved outcomes in critically ill patients with sepsis: a cohort study

B Yang, Y Zhu, X Zheng, T Li, K Niu, Z Wang, X Lu… - Nutrients, 2023 - mdpi.com
Background: Vitamin D, as a common micronutrient, has been widely used in critically ill
patients. However, whether supplementation of vitamin D in adult patients with sepsis can …

Molecular mechanisms of gastrointestinal stromal tumors and their impact on systemic therapy decision

M Unk, B Jezeršek Novaković, S Novaković - Cancers, 2023 - mdpi.com
Simple Summary Gastrointestinal stromal tumors (GISTs) are rare malignancies of the
gastrointestinal tract recognized by their clinical presentation and using specific …

SEOM-GEIS clinical guideline for gastrointestinal stromal tumors (2022)

C Serrano, R Álvarez, JA Carrasco, G Marquina… - Clinical and …, 2023 - Springer
Gastrointestinal stromal tumor (GIST) is the most common malignant neoplasm of
mesenchymal origin, and a paradigmatic model for a successful rational development of …

KIT exon 9-mutated gastrointestinal stromal tumours: biology and treatment

A Napolitano, K Thway, MJ Smith, PH Huang… - Chemotherapy, 2022 - karger.com
Background: The majority of gastroinstestinal stromal tumours (GISTs) harbour oncogenic
mutations in the gene encoding for the tyrosine kinase (TK) KIT. The most common …