Epidemiology, risk factors, and outcomes associated with cytomegalovirus in adult kidney transplant recipients: A systematic literature review of real‐world evidence
AD Raval, KD Kistler, Y Tang, Y Murata… - Transplant Infectious …, 2021 - Wiley Online Library
Kidney transplant recipients (KTRs) have increased risk for cytomegalovirus (CMV)
infection/disease given the necessity of drug‐induced immunosuppression. A …
infection/disease given the necessity of drug‐induced immunosuppression. A …
[HTML][HTML] Milestones in the discovery of antiviral agents: nucleosides and nucleotides
E de Clercq - Acta Pharmaceutica Sinica B, 2012 - Elsevier
In this review article, a number of milestones in the antiviral research field on nucleosides
and nucleotides are reviewed in which the author played a significant part, especially in the …
and nucleotides are reviewed in which the author played a significant part, especially in the …
A direct and indirect comparison meta-analysis on the efficacy of cytomegalovirus preventive strategies in solid organ transplant
DF Florescu, F Qiu, CM Schmidt… - Clinical infectious …, 2014 - academic.oup.com
Background. Prophylactic and preemptive strategies are used to prevent cytomegalovirus
(CMV) infections after solid organ transplant. We assessed the safety and efficacy of both …
(CMV) infections after solid organ transplant. We assessed the safety and efficacy of both …
A systematic review and meta-analysis of optimized CMV preemptive therapy and antiviral prophylaxis for CMV disease prevention in CMV high-risk (D+ R-) kidney …
L Kumar, C Murray-Krezan, N Singh… - Transplantation …, 2023 - journals.lww.com
Background. The optimal strategy for cytomegalovirus (CMV) disease prevention in CMV
donor/recipient kidney transplant recipients remains uncertain. Conclusions of prior meta …
donor/recipient kidney transplant recipients remains uncertain. Conclusions of prior meta …
[HTML][HTML] Primary cytomegalovirus infection significantly impacts circulating T cells in kidney transplant recipients
RWJ Meijers, NHR Litjens, DA Hesselink… - American Journal of …, 2015 - Elsevier
Cytomegalovirus (CMV) infection profoundly affects the T cell compartment and is
associated with alterations in T cell aging parameters and generation of cytotoxic CD4+ …
associated with alterations in T cell aging parameters and generation of cytotoxic CD4+ …
Long-term impact of CMV infection on allografts and on patient survival in renal transplant patients with protocol biopsies
Cytomegalovirus (CMV) infection is a frequent complication of early posttransplantation. This
study examines its impact on chronic allograft changes, long-term graft loss, and patient …
study examines its impact on chronic allograft changes, long-term graft loss, and patient …
Resistant cytomegalovirus infection in solid-organ transplantation: single-center experience, literature review of risk factors, and proposed preventive strategies
Background Cytomegalovirus (CMV) infection causes morbidity and mortality in solid-organ
transplant recipients. Drug-resistant CMV is an emerging problem with poor survival …
transplant recipients. Drug-resistant CMV is an emerging problem with poor survival …
The rationality for using prodrug approach in drug discovery programs for new xenobiotics: opportunities and challenges
NR Srinivas - European journal of drug metabolism and …, 2011 - Springer
The concept of prodrugs has been successfully executed for life cycle management options
of several approved drugs and drugs in development. In addition to imparting ideal …
of several approved drugs and drugs in development. In addition to imparting ideal …
Early cytomegalovirus‐specific T‐cell response and estimated glomerular filtration rate identify patients at high risk of infection after renal transplantation
F Leone, P Gigliotti, MV Mauro, D Lofaro… - Transplant Infectious …, 2016 - Wiley Online Library
Background Assessing the risk of cytomegalovirus (CMV) viremia in kidney transplant
recipients (KTR) may be helpful to indicate in which patient it is worth starting antiviral …
recipients (KTR) may be helpful to indicate in which patient it is worth starting antiviral …
Cytomegalovirus prophylaxis in pediatric kidney transplantation: The D utch experience
H Jongsma, AH Bouts, EAM Cornelissen… - Pediatric …, 2013 - Wiley Online Library
Many children receiving a kidney transplant are seronegative for CMV and therefore, highly
susceptible to a primary CMV infection. This study aims at evaluating incidence, time of …
susceptible to a primary CMV infection. This study aims at evaluating incidence, time of …