Revealing the role of high-density lipoprotein in colorectal cancer

A Zeljkovic, J Vekic, M Mihajlovic, T Gojkovic… - International Journal of …, 2021 - mdpi.com
Colorectal cancer (CRC) is a highly prevalent malignancy with multifactorial etiology, which
includes metabolic alterations as contributors to disease development. Studies have shown …

A hypoxia-related signature for clinically predicting diagnosis, prognosis and immune microenvironment of hepatocellular carcinoma patients

B Zhang, B Tang, J Gao, J Li, L Kong, L Qin - Journal of Translational …, 2020 - Springer
Background Hypoxia plays an indispensable role in the development of hepatocellular
carcinoma (HCC). However, there are few studies on the application of hypoxia molecules in …

The expression and function of circadian rhythm genes in hepatocellular carcinoma

Y Jiang, X Shen, MB Fasae, F Zhi… - Oxidative Medicine …, 2021 - Wiley Online Library
Hepatocellular carcinoma (HCC) is among the most common and lethal form of cancer
worldwide. However, its diagnosis and treatment are still dissatisfactory, due to limitations in …

[HTML][HTML] A pan-cancer analysis of the oncogenic role of secreted phosphoprotein 1 (SPP1) in human cancers

Y Liu, G Ye, B Dong, L Huang, C Zhang… - Annals of …, 2022 - ncbi.nlm.nih.gov
Background Emerging evidence suggests that secreted phosphoprotein 1 (SPP1) is
involved in tumor cell progression in multiple cancer types. However, the role of SPP1 in …

A robust twelve-gene signature for prognosis prediction of hepatocellular carcinoma

G Ouyang, B Yi, G Pan, X Chen - Cancer Cell International, 2020 - Springer
Background The prognosis of hepatocellular carcinoma (HCC) patients remains poor.
Identifying prognostic markers to stratify HCC patients might help to improve their outcomes …

Development and validation of a model including distinct vascular patterns to estimate survival in hepatocellular carcinoma

WP Lin, KL Xing, JC Fu, YH Ling, SH Li… - JAMA network …, 2021 - jamanetwork.com
Importance Because of tumor heterogeneity, traditional clinical variables remain insufficient
to predict recurrence, which impairs long-term survival among patients undergoing radical …

Development of a prognostic model for anoikis and identifies hub genes in hepatocellular carcinoma

Z Zhong, F Xie, J Yin, H Zhao, Y Zhou, K Guo, R Li… - Scientific Reports, 2023 - nature.com
Considering the high fatality of hepatocellular carcinoma (HCC), current prognostic systems
are insufficient to accurately forecast HCC patients' outcomes. In our study, nine anoikis …

A DNA-methylation-driven genes based prognostic signature reveals immune microenvironment in pancreatic cancer

M Xiao, X Liang, Z Yan, J Chen, Y Zhu, Y Xie… - Frontiers in …, 2022 - frontiersin.org
Pancreatic cancer (PACA), which is characterized by an immunosuppressive nature,
remains one of the deadliest malignancies worldwide. Aberrant DNA methylation (DNAm) …

[HTML][HTML] DNA methylation-based lung adenocarcinoma subtypes can predict prognosis, recurrence, and immunotherapeutic implications

F Xu, L He, X Zhan, J Chen, H Xu, X Huang, Y Li… - Aging (albany …, 2020 - ncbi.nlm.nih.gov
The marked heterogeneity of lung adenocarcinoma (LUAD) makes its diagnosis and
treatment difficult. In addition, the aberrant DNA methylation profile contributes to tumor …

DYSF promotes monocyte activation in atherosclerotic cardiovascular disease as a DNA methylation-driven gene

X Zhang, D He, Y Xiang, C Wang, B Liang, B Li… - Translational …, 2022 - Elsevier
Dysferlin (DYSF) has drawn much attention due to its involvement in dysferlinopathy and
was reported to affect monocyte functions in recent studies. However, the role of DYSF in the …